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Advances in Dermatology and Allergology  5/2007

abstract:
 

Review paper
Trophoallergens in the aetiopathogenesis of atopic dermatitis


Post Dermatol Alergol 2007; XXIV, 5: 224–232

authors: Anna Rosińska, Iwona Stajkowska, Wojciech Cichy,


Atopic dermatitis (AD) is a chronic, inflammatory disease, affecting the epidermis and the dermis. AD is a very common disease – it is recognized to affect 5% of children. Trophoallergens, particularly in children, seem to play
a key role in the aetiopathogenesis of AD. Sensitization to food allergens seems to be a triggering factor for the
so-called allergic march phenomenon – from food allergy to AD and then to asthma. Clinical outcome of the disease depends on the immunological system, the age of the child, and whether it was breast-fed or not. Due to the immaturity of the immune and digestive system in infants, breast-feeding up to 4-6 months and avoiding solid food until the 6th month of life are optimal. Recently, a lot of attention has been paid to the possible role of probiotics in the treatment and prevention of inflammatory diseases of intestines and skin.


keywords:
 

AD, infants, food allergy, breastfeeding, nutrition, prevention



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