eISSN: 2299-0054
ISSN: 1895-4588
Videosurgery and Other Miniinvasive Techniques
Current issue Archive Videoforum Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank

vol. 17
Randomized controlled trial

A comparison of the analgesic efficacy of serratus anterior plane block vs paravertebral nerve block for video-assisted thoracic surgery: a randomized controlled trial

Yi Zhang
Ze Fu
Te Fang
Kexin Wang
Zimeng Liu
Hongqing Li
Wenwen Jiang
Xuezhao Cao

Department of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning, China
Videosurgery Miniinv 2022; 17 (1): 134–142
Online publish date: 2021/04/30
Article file
Get citation
JabRef, Mendeley
Papers, Reference Manager, RefWorks, Zotero


Video-assisted thoracic surgery (VATS) is a standard surgical procedure for both minor and major oncological lung surgery. Over 85% patients undergoing VATS often suffer from moderate to severe postoperative pain when coughing and moving [1]. Furthermore, 22% to 63% are converted to chronic pain [2]. Uncontrolled postoperative pain, which is attributed to muscle incisions, rib retractions, and intercostal nerve damage, can result in respiratory complications such as hypoxia and atelectasis, which preclude early recovery [3, 4].

Effective analgesia can alleviate the pain of thoracic surgery, which is provided by thoracic epidural anesthesia (TEA), paravertebral block (PVB), erector spinae plane block (ESPB), serratus anterior plane block (SAPB) and venous analgesia [5]. TEA is the current gold-standard analgesia in thoracotomy. However, TEA has a 30% failure rate, which carries the risk of epidural hematoma or abscess [6]. In recent years, PVB warrants greater attention with its advantages of small trauma, low coagulation requirements, hemodynamic stability and good analgesic effect [7, 8]. However, PVB is not only technically difficult to perform especially in obese patients, but also could be less efficient after pleurodesis due to pleural inflammation or surgical dilaceration of the parietal lining of the pleura [9]. TEA and PVB exhibit certain difficulties with regard to their administration and side effects. Minimally invasive surgery might require less invasive analgesia. Therefore, the clinical standard minimally invasive analgesic technique for VATS is highly recommended.

SAPB, which is less difficult and has fewer severe complications, may be more suitable for VATS [10]. SAPB can completely cover the range of the long thoracic nerve as well as the lateral cutaneous branches of T2 to T5 intercostal nerves, and complement the deficiency of PVB, TEA, and selective intercostal nerve blocks [11]. It is simple to operate, not restricted to the patients who are obese or use anticoagulants, and also exhibited a satisfactory analgesic effect [2, 5, 12, 13]. More recently, a single-center, double-blinded study with 40 patients showed that compared to PVB, SAPB was non-inferior in terms of 48-hour opioid consumption and was associated with improving functional measures in thoracic surgical patients [14]. SAPB can be performed at superficial or deep planes [1517]. Blanco et al. showed that superficial serratus anterior plane block (SSPB) had a wider range and longer block time compared to deep serratus plane block (DSPB) [15]. Conversely, Piracha et al. found that DSPB could relieve the uncontrollable pain of SSPB [16]. However, whether DSPB and SSPB were as good as PVB remained unclear.


The aim of this study is to investigate the analgesic effectiveness of DSPB and SSPB for patients undergoing VATS and the potential for SAPB as an alternative to PVB for VATS.

Material and methods

This prospective, randomized controlled study was performed in Shenyang, after receiving the approval of the institutional ethical committee of the First Hospital of China Medical University and was registered in the Chinese Clinical Trials Registry (Registration No: ChiCTR1900024678). All patients were aged 16–80 years with ASA I or II scheduled for VATS. Patients were excluded as follows: (1) allergy to local anesthetics; (2) ASA III or IV; (3) severe obese patients (BMI > 32 kg/m2); (4) motion sickness; severe cardiorespiratory, hepatic, renal disorders; chronic chest pain; (5) opioid abuse and inability to communicate. According to our preliminary study data, intraoperative opioid consumptions in DSPB, SSPB and PVB groups were 31.22 mg, 34.71 mg and 27.5 mg. 22 patients per group were required to achieve a significance level of 0.05 with a power of 80%. The statistical test used for sample size calculation was one way ANOVA power analysis. Power calculation was completed using PASS (NCSS LLC, Kaysville, Utah). Finally, a total of 74 patients were recruited and provided their written informed consent to participate in this study. They were randomly assigned to receive either DSPB or SSPB as well as PVB.

Data were analyzed using GraphPad Prism 8. Continuous numerical variables were presented as the mean and standard deviation or standard error of the mean, categorical variables were presented as the ratio or as the number and percentage, and between-group differences were compared using Fisher’s exact test (for nominal data) or the chi-squared test for a trend (for ordinal data). Primary and secondary endpoints for each analgesic technique used were compared using the Kruskal-Wallis test with Dunn’s correction. The reported p-value is two-sided. P < 0.05 was considered statistically significant. The Cochran-Armitage test was used for satisfaction score analysis.

Intraoperative management

On arrival in the operating room (OR), after routine ASA monitoring and arranging the patients in the lateral decubitus position with the operative side up, ultrasound-guided nerve block was performed. A 5 µg dose of sufentanil was administered preemptively.

In the DSPB group, a US probe was placed parallel to the midaxillary line at the level of T3-4 and moved laterally to visualize the rib, pleura, front serratus, and latissimus dorsi. A 100the mm blunt-tipped needle was advanced beneath the serratus anterior muscle. Then, saline (1 ml) was injected to confirm the position followed by 20 ml of 0.5% ropivacaine. In the SSPB group, the tip of the needle was advanced to the plane superficial to the serratus anterior muscle. Similarly, a total of 20 ml of 0.5% ropivacaine was injected. In the PVB group, the US probe was placed parallel to the posterior midline at the level of T5 and moved laterally to visualize the transverse process and pleura. In the same way, 20 ml of 0.5% ropivacaine was injected.

General anesthesia was induced after nerve block with propofol 2.0 mg/kg, sufentanil 0.4 µg/kg, cis-atracurium 0.15 mg/kg and dexamethasone 5 mg. Pharyngeal local anesthesia was performed with 3 ml of 2% lidocaine and a double-lumen tube was intubated. The tidal volume (6–8 ml/kg) and the ventilatory frequency were adjusted to maintain an end-tidal carbon dioxide tension of 35–45 mm Hg and airway pressure below 30 cm H2O. Anesthesia was maintained with 2% propofol (30 ml/h) and sevoflurane (0.7–1.5%) to maintain a bispectral index of 40–60. Hypertension was treated with oxycodone hydrochloride 2 mg or Ebrantil 5 mg, oxycodone hydrochloride was used to block sympathetic response to pain. Hypotension was treated with ephedrine 6 mg or phenylephrine 0.1 mg. Bradycardia was treated with atropine 0.3 mg. At the end of the surgery, tropisetron 5 mg was given intravenously to prevent postoperative nausea and vomiting. All patients were transferred to a post-anesthesia care unit (PACU) after surgery. Postoperative analgesia was followed by patient-controlled intravenous analgesia (PCIA). The PCIA regimen consisted of hydromorphone 14 mg mixed with normal saline to a total volume of 150 ml. The disposable PCIA device was set to background infusion of 2 ml/h, demand bolus 6 ml and a 10-min lockout. If patients reported a visual analogue score (VAS score) ≥ 4, flurbiprofen axetil 100 mg was administered every 12 h as a rescue analgesia. If severe nausea or vomiting occurs, we treated the patients with 5 mg tropisetron or stopped PCIA temporarily. After these symptoms reversed, the PCIA restarted.

The primary outcomes were postoperative VAS score, and intraoperative and postoperative opioid consumption. The secondary outcomes included PCIA pressing times, side effects, satisfaction with analgesia, duration of operating nerve block, intraoperative hemodynamic changes and vasoactive drug consumption. VAS scores at rest and on coughing were collected at 12 h, 24 h, 48 h and 72 h postoperatively. The different types of opioids were converted to IV morphine equivalents using the GlobalRPh morphine equivalence calculator at http://www.globalrph.com. Effective and ineffective PCIA pressing times were collected at 12 h, 24 h, 48 h and 72 h postoperatively. The dosage of PCIA was also recorded at the same time. Satisfaction with analgesia in the first 72 postoperative hours was divided into five grades, “highly unsatisfactory”, “unsatisfactory”, “neutral”, “satisfactory”, “highly satisfactory”. Intraoperative hemodynamic changes recorded were the blood pressure and heart rate when the patients entered the OR, before the operation, 5 min after surgical incision, before endotracheal extubation, 5 min after extubation and before leaving the PACU, as well as the duration of intraoperative hypotension. All of the outcomes and perioperative data were collected by an investigator who was blinded to the group allocation.


Patient characteristics

Seventy-four patients were enrolled in the study; 8 were excluded: 1 for VATS conversion to thoracotomy, 1 for secondary thoracotomy on the next day, 6 for stopping using PCIA due to severe nausea and vomiting (3 in SSPB group, 2 in DSPB group, 1 in PVB group). Ultimately, a total of 66 patients completed the study; each group included 22 patients, which is shown in Figure 1. The demographic data, ASA classes, personal history, medical history, and duration of the surgery of the study patients are summarized in Table I. There was no significant difference with respect to the demographic data (p > 0.05).

Table I

Demographic data of 22 patients for each group

ParameterDSPB groupSSPB groupPVB groupP-value
Age [years] mean ± SD55 ±12.5357.95 ±7.6558.64 ±6.780.514
Gender (male) n (%)14 (63.64)11 (50)8 (36.36)0.195
BMI [kg/m2]23.11 ±2.9024.40 ±2.0123.79 ±2.720.275
ASA I (n)141012
ASA II (n)61110
ASA III (n)2100.377
Smoking (n)7970.766
Drinking (n)8740.383
Hypertension (n)5880.533
Diabetes mellitus (n)1320.577
Coronary mellitus (n)1130.421
History of surgery (n)6760.929
Duration of surgery [min]130.82 ±70.28143.18 ±90.23105.32 ±37.980.221

[i] Values of age, BMI and duration of surgery are expressed as mean ± standard deviation.

Figure 1

Flow diagram of the study


Postoperative VAS score

There were no significant differences of VAS scores at rest and on coughing among the three groups at 12 h, 24 h, 48 h, and 72 h postoperatively (Table II). None of the patients suffered severe pain. During the first 24 h postoperatively, the patients presented with mild to moderate pain when coughing (13 in DSPB group, 13 in SSPB group and 17 in PVB group). During the rest of the time, they presented with mild pain.

Table II

Postoperative VAS scores at rest and on coughing

VASDSPB groupSSPB groupPVB groupP-valueP for DSPB group versus SSPB groupP for DSPB group versus PVB groupP for SSPB group versus PVB group
 12 h1.3 [0.8, 1.8]1.6 [0.8, 2.4]1.5 [0.6, 2.4]0.2400.2820.6060.834
 24 h1.1 [0.4, 1.8]1.0 [0.3, 1.7]1.3 [0.7, 19]0.2970.7970.6690297
 48 h0.4 [0.0, 0.9]0.3 [0.0, 0.9]0.5 [0.0, 1.1]0.6620.9600.8500.694
 72 h0.0 [110, 0.0]0.0 [0.0, 0.0]0.1 [0.0, 0.4]0.131> 0.9990.1860.186
 12 h3.5 [2.8, 42]3.8 [3.0, 4.6]3.8 [2.9, 4.7]0.3050.4100.3140.982
 24 h2.9 [13, 4.1]3.0 [2.2, 3.8]3.3 [2.7, 3.9]0.3040.9390.2180.374
 48 h1.6 [0.5, 2.7]1.7 [1.0, 2.4]2.2 [1.5, 2.9]0.0510.9360.0690.143
 72 h0.5 [0.0, 1.0]0.5 [0.0, 1.1]0.9 [0.2, 1.6]0.1650.9670.1270.204

[i] Values are expressed as the mean [95% confidence interval]. When the lower limit value of the 95% confidence interval is less than 0, 0 is used instead. VAS-R – values of VAS scores at rest, VAS-C – values of VAS scores on coughing.

Intraoperative dosage of opioids

Sufentanil and oxycodone hydrochloride were converted to morphine, and the consumption was compared in the three groups. In intergroup comparisons, the PVB group (27.23 ±5.10 mg) was associated with reducing intraoperative opioid consumption compared to the DSPB (31.20 ±3.80 mg) and SSPB group (32.61 ±5.28 mg, p < 0.05). Therefore, PVB had a better analgesic effect than DSPB and SSPB during the operation.

PCIA pressing times and dosage of postoperative analgesics

PCIA pressing times included effective and ineffective times (Table III). During postoperative hours 0–12, there were statistically significant differences for effective pressing times in the DSPB group (1.23 ±1.31), SSPB group (0.77 ±1.00) and PVB group (2.05 ±1.64) (p < 0.05). Moreover, the pressing time in the SSPB group was significantly lower compared to the PVB group (p < 0.05). There was no significant difference in ineffective PCIA pressing times.

Table III

Postoperative analgesics

VASDSPB groupSSPB groupPVB groupP-valueP for DSPB group versus SSPB groupP for DSPB group versus PVB groupP for SSPB group versus PVB group
Effective times:
 0–12 h1.23 ±1.310.77 ±1.002.05 ±1.640.012*0.5190.1260.009*
 12–24 h1.86 ±2.681.09 ±1.932.00 ±2.200.1310.5220.9800.408
 24–48 h0.72 ±1.320.36 ±0.771.09 ±1.500.2100.3200.5990.320
 48–72 h000.05 ±0.210.368> 0.9990.4430.443
Dosage of PCIA [ml]:
 0–12 h27.86 ±6.9226.55 ±4.7231.45 ±7.600.024*0.7910.1840.046*
 12–24 h27.77 ±9.2830.18 ±11.8134.64 ±15.910.8110.4920.1910.492
 24–48 h49.95 ±10.6248.91 ±4.0352.68 ±15.700.7880.9510.7110.522
 48–72 h33.14 ±14.9839.73 ±12.5840.68 ±17.520.0230.3430.2480.977
 Flurbiprofen Axetil [mg]59.09 ±77.8154.55 ±72.1672.73 ±80.800.7440.9800.8350.726

* Significant difference.

Postoperative analgesics included PCIA and flurbiprofen axetil. In the first 12 h postoperatively, the SSPB group had significantly lower PCIA dosage compared with the PVB group (p < 0.05). The maximum dose of flurbiprofen axetil is 100 mg every 12 h. In this study, a maximum of 300 mg was given, which happened in the SSPB group. They was no significant difference in average consumption among the three groups.

Satisfaction with analgesia

There were no significant differences in satisfaction with analgesia in the three groups. Both DSPB and SSPB, as well as PVB, could provide a good analgesic effect postoperatively; eighty percent of the patients showed “neutral” and “satisfactory” approximately. Patients in the PVB group showed more “highly unsatisfactory” and “neutral” than in the DSPB group and the SSPB group.

Side effects

No patient exhibited block-related complications, such as urinary retention, pneumonia, local anesthetic toxicity, bleeding, or infection. The side effects of opioids including nausea, vomiting and dizziness showed no significant differences among the three groups.

Duration of operating nerve block

The duration of operating nerve block, recorded from disinfection to nerve block needle extraction, in all of the groups was done once by the same experienced anesthesiologist. Durations of the DSPB (5.77 ±1.20 min) and SSPB group (4.77 ±1.04 min) were significantly shorter than that of the PVB group (11.14 ±1.66 min, p < 0.05). PVB was more complex for the anesthesiologist to operate.

Intraoperative hemodynamic changes and dosage of vasoactive drugs

Intraoperative blood pressure changes were shown with mean arterial pressure (MAP), which was compared at six time points (Figure 2). At 5 min after the operation, MAP was lower in the PVB group (85.45 ±16 mm Hg) than in the DSPB (99.21 ±15.27 mm Hg, p < 0.05) and SSPB group (104.70 ±16.33 mm Hg, p < 0.05). At 5 min after extubation and before leaving the PACU, the DSPB group showed lower MAP than the SSPB group (p < 0.05). The three groups were comparable regarding the changes of heart rate (Figure 3) and the duration of intraoperative hypotension, which showed no significant differences (p > 0.05).

Figure 2

Intraoperative MAP changes: A – OR admission, B – before operation, C – 5 min after operation, D – before extubation, E – 5 min after extubation, F – after leaving PACU

Figure 3

Intraoperative heart rate changes: A – OR admission, B – before operation, C – 5 min after operation, D – before extubation, E – 5 min after extubation, F – after leaving PACU


Vasoactive drugs included ephedrine, atropine and phenylephrine (Table IV). In-group analyses showed that PVB (0.14 ±0.24 mg) was associated with more intraoperative atropine consumption than DSPB (0 mg, p < 0.05). However, there were no differences in ephedrine and phenylephrine consumption.

Table IV

Intraoperative consumption of vasoactive drugs

VASDSPB groupSSPB groupPVB groupP-valueP for DSPB group versus SSPB groupP for DSPB group versus PVB groupP for SSPB group versus PVB group
Ephedrine [mg]1.91 ±4.571.09 ±2.941.50 ±4.020.8790.7760.9380.938
Atropine [mg]00.05 ±0.210.14 ±0.240.003*0.7080.043*0.225
Phenylephrine [mg]0.33 ±0.730.10 ±0.320.33 ±0.570.1960.407> 0.9990.393

* Significant difference.


This randomized, double-blind study demonstrated that DSPB, SSPB or PVB combined with PCIA reduced the postoperative pain and showed similar satisfaction with analgesia in patients undergoing VATS. Intraoperative opioid consumption remained significantly lower in PVB. SSPB showed lower PCIA pressing times and PCIA dosage than PVB. Furthermore, DSPB and SSPB were easy for the anesthetist to operate, with significantly lower operating duration than PVB. PVB was associated with maintaining hemodynamic stability. However, PVB consumed more atropine intraoperatively.

There were different opinions about the postoperative analgesic effect of DSPB, SSPB and PVB. PVB has long been considered the best possible choice for postoperative analgesia of VATS [18]. In recent studies, SSPB proponents have described successful analgesia without the potentially hazardous need for advancing the needle deeper toward the pleura [15, 17]. However, anatomy arguably favored DSPB, as injection in the fascial plane below the serratus muscle, which blocks the lateral cutaneous branches of the intercostal nerves, might show a better analgesic effect [19]. In our study, DSPB, SSPB and PVB showed similar postoperative analgesic effects, and most patients were satisfied with the analgesic effect. All three can be used for postoperative analgesia of VATS. However, in the early postoperative period (12 h), the SSPB group provided superior pain relief with significantly lower effective PCIA pressing times and dosage compared to the PVB group. Some studies showed that the duration of the sensory blockade produced by SSPB and DSPB was 730–780 min and 380–400 min respectively [2022]. The effective time of PVB persisted for 48 h postoperatively [23]. In our study, the duration of postoperative analgesia for PVB was shorter, probably due to the pharmacological properties of ropivacaine.

During the operation, compared with DSPB and SSPB, PVB showed a superior analgesic effect. PVB significantly decreased intraoperative consumption of opioids compared to DSPB and SSPB, which indicated that the short-term analgesic effect of PVB was better than that of DSPB and SSPB. These findings support observations from previous reports that showed the effectiveness of PVB [24].

The ideal analgesic techniques should not only have a perfect analgesia effect, but also have the advantages of a simple operation, accurate control, high success rate and few complications. The puncture duration of PVB was significantly longer than that of DSPB and SSPB in our study. It might be related to the difference of anatomical position. The serratus anterior muscle was superficial, and could be scanned by a high-frequency linear array ultrasound probe to easily obtain clear images of the serratus anterior muscle and its neighbors. During the puncture, the angle between the needle and skin was small, so the puncture needle could be imaged clearly [25]. Richardson et al. also found that the deep fascia of the serratus anterior muscle had poor adhesion to the intercostal external muscles and was easier to separate than the superficial plane of the serratus anterior muscle, which was also found in our study [26]. The location of the thoracic paravertebral nerve was deeper and should be scanned with a low-frequency convex array probe or high-frequency linear array probe. The puncture needle was difficult to image due to the large angle.

A few studies have shown that the analgesia effect of SSPB was similar to an epidural but perhaps with less hemodynamic instability [17]. In our study, both DSPB and SSPB, as well as PVB, could maintain hemodynamic stability. However, PVB consumed more atropine intraoperatively. Previous studies also have shown that PVB can cause the occurrence of bradycardia and hypotension with a rate of 0.47–2.2%, which might be related to sympathetic block [27].

In addition, the incidence of side effects did not show significant differences among the three groups. There were 6 patients who had motion sickness and reported severe nausea and vomiting. After stopping PCIA, the side effects disappeared, which indicated that they might be associated with the opioid. They withdrew from our study on the basis of the exclusion criteria. We did not observe any complication associated with nerve block, but pneumothorax was potential. The deep surface of the paravertebral area was the pleura, and there was a risk of puncture of the pleura, pneumothorax and other complications. Naja et al. performed PVB in 662 patients, and the probability of developing pneumothorax was about 0.5% [28]. Richardson’s study showed that PVB punctures occasionally entered the epidural space or punctured the pleura, and had a transient occurrence of Horner syndrome [26]. This could explain why many clinicians are reluctant to operate PVB in daily work. Accordingly, patients with a narrow intercostal space, obesity, or poor coagulation function should use DSPB or SSPB.

The present study had several limitations. First, as an observational study, our conclusions might have been limited by inadequate data collection. The pain of the nerve block procedure was not recorded. Meanwhile, due to the time limitation of preoperative preparation, we could only confirm the diffusion of local anesthetics by ultrasound, but did not collect the data of the spread level of analgesia. Second, the research subjects recruited to this study were not treated by the same surgeon, and there were uncontrollable differences. Third, it should be noted that during the operation, when surgeons cut open the skin and subcutaneous tissue of patients who received DSPB or SSPB, it showed a slight edema of subcutaneous tissue, which indicated the possible loss of local anesthetics. Finally, this study did not explore the appropriate local anesthetic dose for nerve block. A study showed that methods of placing a paravertebral catheter (PVC) or an intercostal catheter (ICC) in the sub-pleural space, followed by an infusion pump, were safe and effective analgesic techniques to reduce postoperative pain [29]. In the future, we will conduct further research on the DSPB catheter and SSPB catheter.


DSPB, SSPB or PVB combined with PCIA could provide good postoperative analgesia for patients undergoing VATS. PVB showed a better analgesic effect than DSPB and SSPB intraoperatively. However, the operation of PVB was complex and had potential complications. DSPB or SSPB can serve as a promising alternative to PVB in optimal perioperative pain management in VATS. In future research, large-scale prospective randomized controlled trials are required to compare the efficacy of postoperative analgesia by continuous infusion through a catheter.

Conflict of interest

The authors declare no conflict of interest.



Semyonov M, Fedorina E, Grinshpun J, et al. , authors. Ultrasound-guided serratus anterior plane block for analgesia after thoracic surgery. J Pain Res. 2019. 12:p. 953–60


Okmen K, Okmen BM , authors. Evaluation of the effect of serratus anterior plane block for pain treatment after video-assisted thoracoscopic surgery. Anaesth Crit Care Pain Med. 2018. 37:p. 349–53


Ochroch EA, Gottschalk A , authors. Impact of acute pain and its management for thoracic surgical patients. Thorac Surg Clin. 2005. 15:p. 105–21


Ochroch EA, Gottschalk A, Augostides J, et al. , authors. Long-term pain and activity during recovery from major thoracotomy using thoracic epidural analgesia. Anesthesiology. 2002. 97:p. 1234–44


Park MH, Kim JA, Ahn HJ, et al. , authors. A randomised trial of serratus anterior plane block for analgesia after thoracoscopic surgery. Anaesthesia. 2018. 73:p. 1260–4


Rosero EB, Joshi GP , authors. Nationwide incidence of serious complications of epidural analgesia in the United States. Acta Anaesthesiol Scand. 2016. 60:p. 810–20


Hiro K, Sugiyama T, Kurata M, et al. , authors. Postoperative analgesia for video-assisted thoracoscopic surgery--continuous intravenous infusion of fentanyl combined with intercostal nerve block v.s. continuous epidural analgesia. Masui. 2016. 65:p. 114–8


Scarci M, Joshi A, Attia R , authors. In patients undergoing thoracic surgery is paravertebral block as effective as epidural analgesia for pain management? Interact Cardiovasc Thorac Surg. 2010. 10:p. 92–6


Allain PA, Carella M, Agrafiotis AC, et al. , authors. Comparison of several methods for pain management after video-assisted thoracic surgery for pneumothorax: an observational study. BMC Anesthesiol. 2019. 19:p. 120


Tighe SQ, Karmakar MK , authors. Serratus plane block: do we need to learn another technique for thoracic wall blockade? Anaesthesia. 2013. 68:p. 1103–6


Chu GM, Jarvis GC , authors. Serratus anterior plane block to address postthoracotomy and chest tube-related pain: a report on 3 cases. A A Case Rep. 2017. 8:p. 322–5


Corso RM, Piraccini E, Byrne H, et al. , authors. The serratus anterior plane block for pediatric non-intubated video-assisted thoracoscopic surgery. Minerva Anestesiol. 2017. 83:p. 775–6


Kim DH, Oh YJ, Lee JG, et al. , authors. Efficacy of ultrasound-guided serratus plane block on postoperative quality of recovery and analgesia after video-assisted thoracic surgery: a randomized, triple-blind, placebo-controlled study. Anesth Analg. 2018. 126:p. 1353–61


Hanley C, Wall T, Bukowska I, et al. , authors. Ultrasound-guided continuous deep serratus anterior plane block versus continuous thoracic paravertebral block for perioperative analgesia in videoscopic-assisted thoracic surgery. Eur J Pain. 2020. 24:p. 828–38


Blanco R, Parras T, McDonnell JG, et al. , authors. Serratus plane block: a novel ultrasound-guided thoracic wall nerve block. Anaesthesia. 2013. 68:p. 1107–13


Piracha MM, Thorp SL, Puttanniah V, et al. , authors. “A tale of two planes”: deep versus superficial serratus plane block for postmastectomy pain syndrome. Reg Anesth Pain Med. 2017. 42:p. 259–62


Khalil AE, Abdallah NM, Bashandy GM, et al. , authors. Ultrasound-guided serratus anterior plane block versus thoracic epidural analgesia for thoracotomy pain. J Cardiothorac Vasc Anesth. 2017. 31:p. 152–8


Steinthorsdottir KJ, Wildgaard L, Hansen HJ, et al. , authors. Regional analgesia for video-assisted thoracic surgery: a systematic review. Eur J Cardiothorac Surg. 2014. 45:p. 959–66


Mayes J, Davison E, Panahi P, et al. , authors. An anatomical evaluation of the serratus anterior plane block. Anaesthesia. 2016. 71:p. 1064–9


Bhoi D, Pushparajan HK, Talawar P, et al. , authors. Serratus anterior plane block for breast surgery in a morbidly obese patient. J Clin Anesth. 2016. 33:p. 500–1


López-Matamala B, Fajardo M, Estébanez-Montiel B, et al. , authors. A new thoracic interfascial plane block as anesthesia for difficult weaning due to ribcage pain in critically ill patients. Med Intensiva. 2014. 38:p. 463–5


Madabushi R, Tewari S, Gautam SK, et al. , authors. Serratus anterior plane block: a new analgesic technique for post-thoracotomy pain. Pain Physician. 2015. 18:p. E421–4


Vogt A, Stieger DS, Theurillat C, Curatolo M , authors. Single-injection thoracic paravertebral block for postoperative pain treatment after thoracoscopic surgery. Br J Anaesth. 2005. 95:p. 816–21


Chalam KS, Patnaik SS, Sunil C, et al. , authors. Comparative study of ultrasound-guided paravertebral block with ropivacaine versus bupivacaine for post-operative pain relief in children undergoing thoracotomy for patent ductus arteriosus ligation surgery. Indian J Anaesth. 2015. 59:p. 493–8


Ueshima H, Iwamoto W, Otake H , authors. Serratus plane block for a contraction of the latissimus dorsi muscle. Reg Anesth Pain Med. 2016. 41:p. 411


Richardson J, Lönnqvist PA, Naja Z , authors. Bilateral thoracic paravertebral block: potential and practice. Br J Anaesth. 2011. 106:p. 164–71


Pace MM, Sharma B, Anderson-Dam J, et al. , authors. Ultrasound-guided thoracic paravertebral blockade: a retrospective study of the incidence of complications. Anesth Analg. 2016. 122:p. 1186–91


Naja Z, Lönnqvist PA , authors. Somatic paravertebral nerve blockade. Incidence of failed block and complications. Anaesthesia. 2001. 56:p. 1184–8


Ma H, Song X, Li J, et al. , authors. Postoperative pain control with continuous paravertebral nerve block and intercostal nerve block after two-port video-assisted thoracic surgery. Videosurgery Miniinv. 2021. 16:p. 273–81

Copyright: © 2021 Fundacja Videochirurgii This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Quick links
© 2022 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.