eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
Current issue Archive Manuscripts accepted About the journal Special issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
3/2020
vol. 16
 
Share:
Share:
more
 
 
Cardiology
abstract:
Clinical research

A new electrocardiographic parameter associated with sudden cardiac death in pulmonary sarcoidosis

Samim Emet
1
,
Seda T. Onur
2
,
Sinem N. Sokucu
2
,
Senay Aydin
2
,
Levent Dalar
2
,
Erdogan Cetinkaya
2
,
Imran Onur
1

1.
Department of Cardiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey
2.
Yedikule Chest Disease Training and Research Hospital, Istanbul, Turkey
Arch Med Sci 2020; 16 (3): 559–568
Online publish date: 2019/10/09
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
The interval from the peak to the end of the electrocardiogra­phic T wave (Tp–Te) may correspond to malignant ventricular arrhythmias. In this study we aimed to assess Tp–Te variability and investigate the transmural dispersion of repolarisation in pulmonary sarcoidosis disease without proofed cardiac involvement.

Material and methods
This was a retrospective case-control study that included patients who had a pathologic and radiologic diagnosis of sarcoidosis. All data of the patients’ demographic features and electrocardiographs were analysed.

Results
We enrolled 78 patients with sarcoidosis and 54 healthy volunteers as controls in our study. Men comprised 36% of the sarcoidosis group and 27% of controls. The mean age in the sarcoidosis and control group was 45.4 ±8.7 years (range: 23–58 years) and 44.6 ±11.9 years (range: 21–73 years), respectively. There was no significant difference between the groups for age or sex (p = 0.654, p = 0.246, respectively). There was a significant increase in Tp–Te results in all precordial leads in the sarcoidosis group compared with the control group (p < 0.05).

Conclusions
Pulmonary sarcoidosis is suspected to have cardiac involvement; therefore, we need to develop new approaches. We present strong evidence that Tp–Te intervals were increased in patients with pulmonary sarcoidosis, which suggests that there may be a link between sarcoidosis and ventricular arrhythmias without proofed cardiac involvement.

keywords:

sarcoidosis, ventricular arrhythmia, Tp–Te interval, cardiac involvement

Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe