eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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3/2014
vol. 52
 
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abstract:
Case report

Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis

Anna Masiak
,
Żaneta Smoleńska
,
Zenobia Czuszyńska
,
Zbigniew Zdrojewski

Reumatologia 2014; 52, 3: 207–212
Online publish date: 2014/07/31
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Eosinophilic granulomatosis with polyangiitis (EGPA) characterized by the coexistence of asthma, eosinophilia and characteristic histopathologic changes, is one of the primary systemic small vessel inflammation of unknown etiology. Cardiac involvement in the course of EGPA occur in 17–92% of patients affecting poor prognosis and acting major cause of mortality in this group of patients. EGPA should always be considered in the differential diagnosis of acute heart failure, especially in young patients with no risk factors for coronary heart disease, and in patients with the presence of asthma, allergic rhinitis or nasal polyps. A rare complication of cardiac involvement is the thrombus formation in the left ventricular apex requiring anticoagulation. We report a case of 49 year old man with cardiac involvement that mimic acute coronary syndrome and led to the diagnosis of EGPA.
keywords:

eosinophilic granulomatosis with polyangiitis, acute heart failure, thrombosis





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