eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2021
vol. 38
 
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abstract:
Letter to the Editor

Acute syndrome of apoptotic pan-epidermolysis successfully treated with intravenous immunoglobulin and steroid combination

Nilgun Şentürk
1
,
Enkhjargal Losol
1
,
Yusuf Kelleci
1
,
Hilal Özdemir
1
,
Deniz Bayçelebi
2
,
Levent Yıldız
2

1.
Department of Dermatology, School of Medicine, Ondokuz Mayis University, Kurupelit, Samsun, Turkey
2.
Department of Pathology, School of Medicine, Ondokuz Mayis University, Kurupelit, Samsun, Turkey
Adv Dermatol Allergol 2021; XXXVI (6): 1108-1111
Online publish date: 2022/01/07
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Acute syndrome of apoptotic pan-epidermolysis (ASAP) is a recently described syndrome that is characterized by acute and massive cleavage of the epidermis resulting from hyperacute apoptotic epidermal basal cell injury [1]. This phenomenon is classically seen in drug-induced toxic epidermal necrolysis (TEN), but occasionally occurs in other conditions called ‘TEN-like’ diseases (e.g., lupus erythematosus (LE), acute graft versus host disease (GVHD) and pseudoporphyria) [2, 3].
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