Postępy Dermatologii i Alergologii

Abstract

6/2021 vol. 38
Letter to the Editor

Acute syndrome of apoptotic pan-epidermolysis successfully treated with intravenous immunoglobulin and steroid combination

  1. Department of Dermatology, School of Medicine, Ondokuz Mayis University, Kurupelit, Samsun, Turkey
  2. Department of Pathology, School of Medicine, Ondokuz Mayis University, Kurupelit, Samsun, Turkey
Adv Dermatol Allergol 2021; XXXVI (6): 1108-1111
Online publish date: 2022/01/07
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Acute syndrome of apoptotic pan-epidermolysis (ASAP) is a recently described syndrome that is characterized by acute and massive cleavage of the epidermis resulting from hyperacute apoptotic epidermal basal cell injury [1]. This phenomenon is classically seen in drug-induced toxic epidermal necrolysis (TEN), but occasionally occurs in other conditions called ‘TEN-like’ diseases (e.g., lupus erythematosus (LE), acute graft versus host disease (GVHD) and pseudoporphyria) [2, 3].
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