Postępy Dermatologii i Alergologii

Full text

5/2026 vol. 43
Letter to the Editor

Allergic contact dermatitis caused by tetracaine: two case reports and literature review

Marinella Viola 1
,
Caterina Sarnari 2
,
Michele Centrone 1
,
Rosy De Dominicis 1
,
Angela Rizzi 1

  1. Allergy and Clinical Immunology Unit, Medical and Surgical Sciences Department, IRCCS “A. Gemelli” Universitary Hospital Foundation, Rome, Italy

  2. Pediatric Allergy Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy

Adv Dermatol Allergol 2026; XLIII (5): 588-591

DOI: https://doi.org/10.5114/ada.2026.165992
Data publikacji online: 2026/10/23
Article file
PDiA Allergic.pdf
  1. Johansen JD, Aalto-Korte K, Agner T, et al. European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice. Contact Dermatitis 2015; 73: 195-221.
  2. Brockow K, Garvey LH, Aberer W, et al.; ENDA/EAACI Drug Allergy Interest Group. Skin test concentrations for systemically administered drugs – an ENDA/EAACI Drug Allergy Interest Group position paper. Allergy 2013; 68: 702-12.
  3. Amado A, Sood A, Taylor JS. Contact allergy to lidocaine: a report of sixteen cases. Dermatitis 2007; 18: 215-20.
  4. Brockow K, Ardern-Jones MR, Mockenhaupt M, et al. EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity. Allergy 2019; 74: 14-27.
  5. Connolly M, Mehta A, Sansom JE, et al. Allergic contact dermatitis from tetracaine in the beauty industry. Contact Dermatitis 2004; 51: 95-6.
  6. Dawe RS, Watt D, O’Neill, et al. A laser-clinic nurse with allergic contact dermatitis from tetracaine. Contact Dermatitis 2002; 46: 306.
  7. Opstrup MS, Sørensen HB, Zachariae C. Occupational allergic contact dermatitis caused by tetracaine in an otorhinolaryngologist. Contact Dermatitis 2017; 76: 55-7.
  8. Garcıa Perez A, Conde´Salazar L, Guimaraens D, et al. La sensibilidad de contacto a ametocaina. Actas Dermosifiliogr 1981; 72: 441-8.
  9. Rebandel P, Rudzki E. Occupational contact sensitivity in oculists. Contact Dermatitis 1986; 15: 92.
  10. Dannaker CJ, Maibach HI, Austin E. Allergic contact dermatitis to proparacaine with subsequent cross-sensitization to tetracaine from ophthalmic preparations. Am J Contact Derm 2001; 12: 177-9.
  11. Condé-Salazar L, Llinás MG, Guimaraens D, et al. Occupational allergic contact dermatitis from amethocaine. Contact Dermatitis 1988; 19: 69-70.
  12. García-Gavín J, Alonso-González J, Gutiérrez-González E, et al. Allergic contact dermatitis caused by tetracaine contained in otic drops. Contact Dermatitis 2011; 65: 175-6.
  13. Lodi A, Ambonati M, Coassini A, et al. Contact allergy to ‘caines’ caused by anti-hemorrhoidal ointments. Contact Dermatitis 1999; 41: 221-2.
  14. Matos-Pires E, Pina-Trincão D, Brás S, et al. Baboon syndrome caused by anti-haemorrhoidal ointment. Contact Dermatitis 2018; 78: 170-1.
  15. Sánchez-Pérez J, Córdoba S, Cortizas CF, et al. Allergic contact balanitis due to tetracaine (amethocaine) hydrochloride. Contact Dermatitis 1998; 39: 268.
  16. Villarreal LC, de Frutos FJ, Del Prado Sánchez Caminero M, et al. Perineal allergic contact dermatitis due to tetracaine in a urological lubricant. Contact Dermatitis 2004; 51: 321-2.
  17. Hernández-Machín B, Schamann F, Hernández B, et al. Allergic contact dermatitis to a urologic lubricant. Dermatitis 2005; 16: 142-4.
  18. Channual J, Wu JJ, Zachary CB. Localized contact urticaria caused by lidocaine/tetracaine peel. Arch Dermatol 2009; 145: 499-500.
  19. Taddio A, Lee CM, Parvez B, et al. Contact dermatitis and bradycardia in a preterm infant given tetracaine 4% gel. Ther Drug Monit 2006; 28: 291-4.
  20. Fernández-Redondo V, León A, Santiago T, et al. Allergic contact dermatitis from local anaesthetic on peristomal skin. Contact Dermatitis 2001; 45: 358.
  21. Wilkinson M, Gonçalo M, Aerts O, et al. The European baseline series and recommended additions: 2019. Contact Dermatitis 2019; 80: 1-4.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
SUBMIT YOUR PAPER
Share
without publication fees
Indexed in
pubmed
Integrated with
integrated with publons
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications