ORIGINAL PAPER
An assessment of exercise tolerance in normobaric hypoxia of patients with diabetes mellitus type 1
 
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Department of Physiological-Medical Sciences, the Jerzy Kukuczka University of Physical Education, Katowice, Poland
 
 
Online publication date: 2018-04-12
 
 
Hum Mov. 2014;15(3):171-176
 
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ABSTRACT
Purpose:
Physical activity is an integral part of the treatment of diabetes. The aim of the study was to assess aerobic capacity and cardiovascular-respiratory reactions to a single physical exercise with gradually increasing intensity in normobaric hypoxia in patients with Type 1 diabetes.

Methods:
The study was conducted on a sample of adults with Type 1 diabetes (GT1D, n = 13) and a randomly chosen healthy control (GK, n = 15). The study participants performed a progressive exercise test to exhaustion in normoxia (FiO2 ~ 20.90%) and 7 days later in normobaric hypoxia (FiO2 ~ 15.14%). At rest, during exercise, and after completion of the test blood was drawn and physiological indicators were monitored.

Results:
Two-way ANOVA revealed a significant effect of hypoxia and physical exercise on blood glucose concentrations (F = 6.1 p < 0.01). In GT1D , lower glucose levels were observed in normobaric hypoxia compared with baseline and post-exercise levels in normoxia (p < 0.05). A tendency to increased maximal oxygen uptake and significantly higher minute pulmonary ventilation was observed in both groups in response to exercise and hypoxia.

Conclusions:
Physical activity and hypoxia may effectively control glucose homeostasis and increase cardiorespiratory adaptation to exercise in Type 1 diabetics.

ISSN:1899-1955
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