eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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SCImago Journal & Country Rank
1/2021
vol. 46
 
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abstract:
Case report

Anorexia nervosa and juvenile lupus erythematosus in a 16-year-old female patient – common disease origin or random coincidence?

Lidia Hyla-Klekot
1
,
Agnieszka Wolny
1
,
Małgorzata Janas-Kozik
2, 3
,
Tomasz Koszutski
1

1.
Department of Pediatric Surgery and Urology, Medical University of Silesia, Katowice, Poland
2.
John Paul II’s Pediatric Centre in Sosnowiec, Sosnowiec, Poland
3.
Clinical Ward of Developmental Age Psychiatry and Psychotherapy, Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Cent Eur J Immunol 2021; 46 (1): 127-132
Online publish date: 2021/03/11
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Adolescence is a period in which eating disorders and juvenile systemic lupus erythematosus are typically diagnosed. The coexistence of both disorders prompts the search for a common aetiology.

In this paper, we present a case of a 16-year-old girl with life-threatening anorexia nervosa followed by clinical and immunological manifestations of systemic lupus erythematosus. The severity of the symptoms of anorexia nervosa resulted in significant delay in proper diagnosis of the concomitant systemic disease which had already been active. The administration of immunosuppressive treatment resulted in decreased lupus activity and resolution of the symptoms of anorexia nervosa. Being affected by one severe and chronic disease does not preclude the coexistence of another disease of different aetiology. However, such coexistence may suggest a common pathophysiology. Many authors have indicated a possible link between anorexia nervosa and many autoimmune disorders. Currently, modern genetic techniques have confirmed a significant correlation between these disorders. This issue needs further investigation and may be helpful in arriving at the final diagnosis in similar cases.
keywords:

anorexia nervosa, systemic lupus erythematosus (SLE), immunosuppressive therapy

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