eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2019
vol. 36
 
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abstract:
Original paper

Anti-inflammatory activity of Anthemis tricolor Boiss

Serkan Demirkan
,
Özge Özçınar
,
Bijen Kıvçak

Adv Dermatol Allergol 2019; XXXVI (6): 677-680
Online publish date: 2019/12/30
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Introduction
Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemis species such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties.

Aim
Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts.

Material and methods
Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolor Bois showed significantly reduced erythema compared to the negative control.

Results
Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect.

Conclusions
This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity.

keywords:

Anthemis tricolor, anti-inflammatory, n-hexane, sesquiterpene, minimal erythema dose

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