eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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6/2018
vol. 35
 
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abstract:
Review paper

Antibiotic resistance and NG-MAST sequence types of Neisseria gonorrhoeae isolates in Poland compared to the world

Beata Młynarczyk-Bonikowska, Magdalena Malejczyk, Sławomir Majewski, Magnus Unemo

Adv Dermatol Alllergol 2018; XXXV (6): 546-551
Online publish date: 2018/11/26
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Gonorrhoea is one of the most common sexually transmitted infections and in 2012, the World Health Organization estimated about 78 million of new global urogenital cases among adults per year. The main concern during the latest decade has been the emergence and spread of multidrug-resistant strains of Neisseria gonorrhoeae. Resistance has emerged internationally to the extended-spectrum cephalosporins, ceftriaxone and cefixime, which are the last remaining options for empiric first-line monotherapy of gonorrhoea. In Poland, the levels of resistance to ciprofloxacin, benzylpenicillin and tetracycline are high, and the prevalence of azithromycin resistance has increased. However, no resistance to ceftriaxone has been identified. The currently spread multidrug-resistant strains frequently represent epidemic clones. The present paper reviews and describes the antimicrobial resistance and N. gonorrhoeae multiantigen sequence typing (NG-MAST) sequence types of N. gonorrhoeae strains spreading in Poland compared to the world.
keywords:

Neisseria gonorrhoeae, gonorrhoea, antimicrobial resistance, ceftriaxone, azithromycin, NG-MAST, sequence type, genogroup

references:
Newman L, Rowley J, Vander Hoorn S, et al. Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting. PLoSOne 2015; 10: e0143304.
Mlynarczyk-Bonikowska B, Skulska E, Malejczyk M, et al. Nucleic acid amplification methods in laboratory diagnostics of selected sexually transmitted diseases. Post Mikrobiol 2015; 54: 407-14.
Unemo M, Shafer WM. Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future. Clin Microbiol Rev 2014; 27: 587-613.
Shimuta K, Watanabe Y, Nakayama S, et al. Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan. BMC Infect Dis 2015; 15: 378.
Wi T, Lahra MM, Ndowa F, et al. Antimicrobial resistance in Neisseria gonorrhoeae: global surveillance and a call for international collaborative action. PLoS Med 2017; 14: e1002344.
World Health Organization. Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics, publications/global-priority-list-antibiotic-resistant-bacteria/en/Geneva 2017; http://www.who.int/medicines/
Unemo M, Ringlander J, Wiggins C, et al. High in vitro susceptibility to the novel spiropyrimidinetrione AZD0914 among contemporary clinical Neisseria gonorrhoeae isolates in 21 European countries. Antimicrob Agents Chemother 2015; 59: 5220-5.
Mlynarczyk-Bonikowska B, Serwin AB, Golparian D, et al. Epidemiology, antimicrobial susceptibility/resistance and genetic characteristics of Neisseria gonorrhoeae isolates from Poland, 2010-2012. BMC Infect Dis 2014; 14: 65.
Mlynarczyk-Bonikowska B, Kujawa M, Mlynarczyk G, et al. Susceptibility to ceftriaxone and penicillinase plasmids of Neisseria gonorrhoeae strains isolated in Poland in 2012-2013. Folia Microbiol 2016; 61: 269-73.
European Centre for Disease Prevention and Control. Gonococcal antimicrobial susceptibility surveillance in Europe, 2014. Stockholm: ECDC. 2016.
Mlynarczyk-Bonikowska B, Kujawa M, Mlynarczyk G, et al. Resistance to azithromycin of Neisseria gonorrhoeae strains isolated in Poland in 2012-2013 years. Med Dośw Mikrobiol 2014; 66: 209-14.
Jacobsson S, Golparian D, Cole M, et al. Whole genome sequence analysis and molecular resistance mechanisms in azithromycin resistant Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. J Antimicrob Chemother 2016; 71: 3109-16.
Mlynarczyk-Bonikowska B, Kujawa M, Mlynarczyk G, et al. Resistance to ciprofloxacin of Neisseria gonorrhoeae strains isolated in Poland in 2012-2013. Med Dośw Mikrobiol 2014; 66: 99-104.
Mlynarczyk-Bonikowska B, Przedpełska G, Malejczyk M, et al. Penicillinase production by Neisseria gonorrhoeae strains isolated from the patients of Dermatology and Wenerology Clinic, Warsaw Medical University in 2006–2009. Med Dośw Mikrobiol 2011; 63: 115-20.
Mlynarczyk-Bonikowska B, Kujawa M, Malejczyk M, et al. Plasmid-mediated resistance to tetracyclines among Neisseria gonorrhoeae strains isolated in Poland in the period 2012–2013. Post Dermatol Alergol 2016; 33: 475-9.
Ohnishi M, Golparian D, Shimuta K, et al. Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea? Detailed characterization of the first strain with high-level resistance to ceftriaxone. Antimicrob Agents Chemother 2011; 55: 3538-45.
Ohnishi M, Saika T, Hoshina S, et al. Ceftriaxone-resistant Neisseria gonorrhoeae, Japan. Emerg Infect Dis 2011; 17: 148-9.
Unemo M, Golparian D, Nicholas R, et al. High-level cefixime- and ceftriaxone-resistant N. gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother 2012; 56: 1273-80.
Cámara J, Serra J, Ayats J, et al. Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain. J Antimicrob Chemother 2012; 67: 1858-60.
Shimuta K, Unemo M, Nakayama S, et al. Antimicrobial resistance and molecular typing of Neisseria gonorrhoeae isolates in Kyoto and Osaka, Japan, 2010 to 2012: intensified surveillance after identification of the first strain (H041) with high-level ceftriaxone resistance. Antimicrob Agents Chemother 2013; 57: 5225-32.
European Centre for Disease Prevention and Control. Gonococcal antimicrobial susceptibility surveillance in Europe, 2012. Stockholm: ECDC. 2014.
European Centre for Disease Prevention and Control. Gonococcal antimicrobial susceptibility surveillance in Europe, 2013. Stockholm: ECDC. 2015.
Cole MJ, Spiteri G, Jacobsson S, et al. Overall low extended-spectrum cephalosporin resistance but high azithromycin resistance in Neisseria gonorrhoeae in 24 european countries, 2015. BMC Infect Dis 2017; 17: 617.
Cole MJ, Spiteri G, Jacobsson S, et al. Is the tide turning again for cephalosporin resistance in Neisseria gonorrhoeae in Europe? Results from the 2013 European surveillance. BMC Infect Dis 2015; 15: 321.
Cole MJ, Spiteri G, Chisholm SA, et al. Emerging cephalosporin and multidrug-resistant gonorrhoea in Europe. Euro Surveill 2014; 19: 20955.
Cole MJ, Unemo M, Hoffmann S, et al. The European gonococcal antimicrobial surveillance programme, 2009. Euro Surveill 2011; 16: pii: 19995.
Vincent LR, Kerr SR, Tan Y, et al. In vivo-selected compensatory mutations restore the fitness cost of mosaic penA alleles that confer ceftriaxone resistance in Neisseria gonorrhoeae. MBio 2018; 9: pii: e01905-17.
Lahra MM, Ryder N, Whiley DM. A new multidrug-resistant strain of Neisseria gonorrhoeae in Australia. N Engl J Med 2014; 371: 1850-1.
Lahra MM, Martin I, Demczuk W, et al. Cooperative recognition of internationally disseminated ceftriaxone-resistant Neisseria gonorrhoeae strain. Emerg Infect Dis 2018; 24: 735-40.
Gianecini R, Oviedo C, Stafforini G, et al. Neisseria gonorrhoeae resistant to ceftriaxone and cefixime, Argentina. Emerg Infect Dis 2016; 22: 1139-41.
Deguchi T, Yasuda M, Hatazaki K, et al. New clinical strain of Neisseria gonorrhoeae with decreased susceptibility to ceftriaxone, Japan. Emerging Infect Dis 2016; 22: 142-4.
Nakayama SI, Shimuta K, Furubayashi KI, et al. New ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain with a novel mosaic penA gene isolated in Japan. Antimicrob Agents Chemother 2016; 60: 4339-41.
Terkelsen D, Tolstrup J, Johnsen CH, et al. Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. Euro Surveill 2017; 22. doi: 10.2807/1560-7917.
Lefebvre B, Martin I, Demczuk W, et al. Ceftriaxone-resistant Neisseria gonorrhoeae, Canada, 2017. Emerging Infect Dis 2018; 24: 381-3.
Chen SC, Yin YP, Dai XQ, et al. Antimicrobial resistance, genetic resistance determinants for ceftriaxone and molecular epidemiology of Neisseria gonorrhoeae isolates in Nanjing, China. J Antimicrob Chemother 2016; 69: 2959-65.
Chen SC, Yin YP, Dai XQ, et al. First nationwide study regarding ceftriaxone resistance and molecular epidemiology of Neisseria gonorrhoeae in China. J Antimicrob Chemother 2016; 71: 92-9.
Yin YP, Han Y, Dai XQ, et al. Susceptibility of Neisseria gonorrhoeae to azithromycin and ceftriaxone in China: a retrospective study of national surveillance data from 2013 to 2016. PLoS Med 2018; 15: e1002499.
Yasuda M, Hatazaki K, Ito S, et al. Antimicrobial susceptibility of Neisseria gonorrhoeae in Japan from 2000 to 2015. Sex Transm Dis 2017; 44: 149-53.
Public Health England. Update on investigation of UK case of Neisseria gonorrhoeae with high-level resistance to azithromycin and resistance to ceftriaxone acquired abroad. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/701185/hpr1418_MDRGC.pdf
Australian Government. Department of Health. Multi-drug resistant gonorrhoea 2018. http://www.health.gov.au/internet/main/publishing.nsf/Content/mr-yr18-dept-dept004.htm.
Bignell C, Unemo M. European STI Guidelines Editorial Board. 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults. Int J STD AIDS 2013; 24: 85-92.
Kubanov A, Vorobyev D, Chestkov A, et al. Molecular epidemiology of drug-resistant Neisseria gonorrhoeae in Russia (Current Status, 2015). BMC Infect Dis 2016; 16: 389.
43. Lebedzeu F, Golparian D, Titov L, et al. Antimicrobial susceptibility/resistance and NG-MAST characterization of Neisseria gonorrhoeae in Belarus, Eastern Europe, 2010-2013. BMC Infect Dis 2015; 15: 29.
Kubanova A, Kubanov A, Frigo N, et al. Russian gonococcal antimicrobial susceptibility programme (RU-GASP): resistance in Neisseria gonorrhoeae during 2009-2012 and NG-MAST genotypes in 2011 and 2012. BMC Infect Dis 2014; 14: 342.
European Centre for Disease Prevention and Control. Gonococcal antimicrobial susceptibility surveillance in Europe, 2015. Stockholm: ECDC. 2017.
Unemo M, Dillon JA. Review and international recommendation of methods for typing Neisseria gonorrhoeae isolates and their implications for improved knowledge of gonococcal epidemiology, treatment, and biology. Clin Microbiol Rev 2011; 24: 447-58.
Unemo M, Dillon JA. Mitigating the emergence and spread of multidrug- and extensively drug-resistant gonorrhoea: is there sufficient support in resource-poor settings in Africa? Sex Transm Dis 2014; 41: 238-39.
Martin IM, Ison CA, Aanensen DM, et al. Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area. J Infect Dis 2004; 189: 1497-505.
Jiang FX, Lan Q, Le WJ, et al. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014–2015): genetic characteristics of antimicrobial resistance. BMC Infect Dis 2017; 17: 366.
Demczuk W, Lynch T, Martin I, et al. Whole-genome phylogenomic heterogeneity of Neisseria gonorrhoeae isolates with decreased cephalosporin susceptibility collected in Canada between 1989 and 2013. J Clin Microbiol 2015; 53: 191-200.
National Surveillance of Antimicrobial Susceptibilities of Neisseria gonorrhoeae Annual Summary 2014. Public Health Agency of Canada 2015; 1-45.
Demczuk W, Sidhu S, Unemo M, et al. Neisseria gonorrhoeae sequence typing for antimicrobial resistance, a novel antimicrobial resistance multilocus typing scheme for tracking global dissemination of N. gonorrhoeae strains. J Clin Microbiol 2017; 55: 1454-68.
O’Reilly LC, Goire N, Fisk RE, et al. Molecular epidemiology of Neisseria gonorrhoeae using multi-antigen sequence typing and pulse-field gel electrophoresis in highly endemic Western Australian populations. BMC Infect Dis 2015; 15: 272.
European Centre for Disease Prevention and Control. Molecular typing of Neisseria gonorrhoeae – results from a pilot study 2010–2011. Stockholm: ECDC, 2012.
European Centre for Disease Prevention and Control. Molecular typing of Neisseria gonorrhoeae – study 2013. Stockholm: ECDC, 2016.
Gose S, Nguyen D, Lowenberg D, et al. Neisseria gonorrhoeae and extended-spectrum cephalosporins in California: surveillance and molecular detection of mosaic penA. BMC Infect Dis 2013; 13: 570.
Jabeen K, Bhawan Mal P, Khan E, et al. Antimicrobial resistance and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) genotypes in N. gonorrhoeae during 2012–2014 in Karachi, Pakistan. BMC Infect Dis 2016; 16: 353.
Chisholm SA, Unemo M, Quaye N, et al. Molecular epidemiological typing within the European Gonococcal Antimicrobial Resistance Surveillance Programme reveals predominance of a multidrug-resistant clone. Euro Surveill 2013; 18: pii: 20358.
Grad YH, Kirkcaldy RD, Trees D, et al. Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study. Lancet Infect Dis 2014; 14: 220-6.
Harris SR, Cole MJ, Spiteri G, et al. European survey of Neisseria gonorrhoeae using whole genome sequencing identified spread of multidrug-resistant clones and provides a foundation for genomic surveillance – an observational study. Lancet Infect Dis 2018; 18: 758-68.
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