eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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3/2013
vol. 51
 
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abstract:
Editorial

Antinuclear antibodies – what to do with them?

Mariusz Puszczewicz

Reumatologia 2013; 51, 3: 172-178
Online publish date: 2013/06/26
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Diagnosis of nearly all systemic inflammatory connective tissue diseases requires confirmation of the presence of autoantibodies. In clinical practice, usually for this purpose antinuclear antibodies (ANA) are used.

The paper presents the diagnostic and prognostic significance of antinuclear antibodies. The author presents the current proposals for the nomenclature of ANA and their clinical significance. Additionally he discusses rare types of fluorescence of nuclei and cytoplasm of HEp-2 cells of which the diagnostic and clinical significance has not been discussed yet.
keywords:

indirect immunofluorescence method, antinuclear antibodies, “rings and rods” pattern



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