ISSN: 2451-0637
Archives of Medical Science - Civilization Diseases
Current volume Archive About the journal Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
 
1/2019
vol. 4
 
Share:
Share:
more
 
 
abstract:
Clinical research

Antithrombotic/antiplatelet therapy and colonoscopy results in patients over 50 with iron-deficiency anemia

Tolga Olmez
1
,
Hilmi Bozkurt
1
,
Selcuk Gulmez
1
,
Emre Aray
1
,
Zeliha Ozlem Sert
1
,
Esin Kaplan
1
,
Can Ibrahim Bulut
1
,
Erdal Karakose
1
,
Erdal Polat
1
,
Mustafa Duman
1

1.
Department of Gastrointestinal Surgery, Kartal Kosuyolu High Speciality and Training Hospital, Istanbul, Turkey
Arch Med Sci Civil Dis 2019; 4: e28–e33
Online publish date: 2019/07/18
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
PlumX metrics:
Introduction
This study aims to evaluate the results of asymptomatic patients who have been using anticoagulant-antiaggregant (AC-AA) agents and have had colonoscopy screening due to iron-deficiency anemia (IDA).

Material and methods
The data of 347 asymptomatic patients over the age of 50, who have received colonoscopy due to IDA, were reviewed retrospectively. The effects of sex and AC-AA administration on positive colonoscopy results, preneoplastic lesions and malignancy were investigated.

Results
Of 347 patients over 50 with IDA, 204 were female (58.8%). The mean age was 63.4 ±8.4. Positive colonoscopy results were observed more commonly in 69 male patients compared to 67 female patients (p = 0.004). Similarly, positive colonoscopy results were found to be more frequent among patients using AC-AA (p = 0.019). While premalignant lesions were more frequently diagnosed in male patients (23% to 10.2%), the results were also statistically significant (p = 0.002). Anticoagulant administration did not contribute to the increase in preneoplastic lesion rates (15.57% to 15.55%). Malignant pathology, which was seen in 8 male patients, was more common among male patients yet it was not statistically significant (p = 0.081). However, compared to 3 patients who did not use AC-AA, malignant pathology was seen more frequently in 9 patients who were on AC-AA and the figure was statistically significant (p = 0.009).

Conclusions
The AC-AA administration in asymptomatic patients over 50 with IDA who have had colonoscopy screening increases the rate of colorectal malignancy diagnosis, while it leads to no change in the rate of preneoplastic lesion detection. Nevertheless, male sex is a factor that increases the possibility of preneoplastic lesion detection.

keywords:

colonoscopy, iron deficiency anemia, antithrombotic

Quick links
© 2023 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.