Abstract
5/2007
vol. 24
Review paperTrophoallergens in the aetiopathogenesis of atopic dermatitis
Post Dermatol Alergol 2007; XXIV, 5: 224–232
Online publish date: 2007/10/22
Atopic dermatitis (AD) is a chronic, inflammatory disease, affecting the epidermis and the dermis. AD is a very common disease – it is recognized to affect 5% of children. Trophoallergens, particularly in children, seem to play
a key role in the aetiopathogenesis of AD. Sensitization to food allergens seems to be a triggering factor for the
so-called allergic march phenomenon – from food allergy to AD and then to asthma. Clinical outcome of the disease depends on the immunological system, the age of the child, and whether it was breast-fed or not. Due to the immaturity of the immune and digestive system in infants, breast-feeding up to 4-6 months and avoiding solid food until the 6th month of life are optimal. Recently, a lot of attention has been paid to the possible role of probiotics in the treatment and prevention of inflammatory diseases of intestines and skin.
a key role in the aetiopathogenesis of AD. Sensitization to food allergens seems to be a triggering factor for the
so-called allergic march phenomenon – from food allergy to AD and then to asthma. Clinical outcome of the disease depends on the immunological system, the age of the child, and whether it was breast-fed or not. Due to the immaturity of the immune and digestive system in infants, breast-feeding up to 4-6 months and avoiding solid food until the 6th month of life are optimal. Recently, a lot of attention has been paid to the possible role of probiotics in the treatment and prevention of inflammatory diseases of intestines and skin.
Keywords
AD, infants, food allergy, breastfeeding, nutrition, prevention
Integrated with