Advances in Dermatology and Allergology
eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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Letter to the Editor

Assessment of adalimumab used in a patient with hemorrhagic rheumatoid neutrophilic dermatosis

Tianqi Wei
1
,
Zhimin Duan
1
,
Hao Chen
1
,
Zhi Xiang
1
,
Chengrang Li
1

  1. Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China
Adv Dermatol Allergol
DOI: https://doi.org/10.5114/ada.2026.159113
Online publish date: 2026/02/06
Article file
- Assessment.pdf  [0.16 MB]
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1. Turesson C, O’Fallon WM, Crowson CS, et al. Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years. Ann Rheum Dis 2003; 62: 722-7.
2. Ziemer M, Muller AK, Hein G, et al. Incidence and classification of cutaneous manifestations in rheumatoid arthritis. J Dtsch Dermatol Ges 2016; 14: 1237-46.
3. Kreuter A, Rose C, Zillikens D, Altmeyer P. Bullous rheumatoid neutrophilic dermatosis. J Am Acad Dermatol 2005; 52: 916-8.
4. Scotti B, Misciali C, Merli Y, et al. Rheumatoid neutrophilic dermatitis. J Eur Acad Dermatol Venereol 2024; 3: 1364-80.
5. Chen YF, Jobanputra P, Barton P, et al. A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness. Health Technol Assess 2006; 10: iii-229.
6. den Broeder AA, Wanten GJ, Oyen WJ, et al. Neutrophil migration and production of reactive oxygen species during treatment with a fully human anti-tumor necrosis factor-alpha monoclonal antibody in patients with rheumatoid arthritis. J Rheumatol 2003; 30: 232-7.
7. Grivennikov SI, Tumanov AV, Liepinsh DJ, et al. Distinct and nonredundant in vivo functions of TNF produced by T cells and macrophages/neutrophils: protective and deleterious effects. Immunity 2005; 22: 93-104.
8. Manoj H, Gomes SM, Thimmappa PY, et al. Cytokine signalling in formation of neutrophil extracellular traps: implications for health and diseases. Cytokine Growth Factor Rev 2025; 81: 27-39.
9. Lee KH, Kronbichler A, Park DD, et al. Neutrophil extracellular traps (NETs) in autoimmune diseases: a comprehensive review. Autoimmun Rev 2017; 16: 1160-73.
10. James M, Sioletic S, Creamer D. A papular eruption on the elbows in a patient with rheumatoid arthritis. Clin Exp Dermatol 2021; 46: 1633-7.
11. Stephenson SR, Campbell SM, Drew GS, Magro CM. Palisaded neutrophilic and granulomatous dermatitis presenting in a patient with rheumatoid arthritis on adalimumab. J Cutan Pathol 2011; 38: 644-8.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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