Advances in Dermatology and Allergology
eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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2/2025
vol. 42
 
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abstract:
Review paper

Atopic dermatitis and non-alcoholic fatty liver disease: current state of evidence and possible pathogenetic correlations

Marta Dębicka
1
,
Aleksandra Bąk
2
,
Jerzy Walecki
1
,
Irena Walecka
2

  1. Centre of radiological Diagnostics, The National Institute of Medicine of the Ministry of the Interior and Administration, Warsaw, Poland
  2. Dermatology Department, The National Institute of Medicine of the Ministry of the Interior and Administration, Warsaw, Poland
Adv Dermatol Allergol 2025; XLII (2): 121-124
DOI: https://doi.org/10.5114/ada.2025.149546
Online publish date: 2025/04/15
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Relationships between inflammatory diseases and metabolic abnormalities are recently raising much scientific interest. Convincing evidence on the association between atopic dermatitis (AD) and constituents of metabolic syndrome (MS) has already been established. In this article we aim to summarize current data on the link between AD and non-alcoholic fatty liver disease (NAFLD), which is considered a hepatic manifestation of MS. By reviewing animal models, human studies and possible pathogenetic points of contiguity we want to present the current state of knowledge and goals for further investigations. To our best knowledge, this is the first review of this topic so far.
keywords:

atopic dermatitis, non-alcoholic fatty liver disease, liver steatosis, gut-skin axis
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