Polish Journal of Pathology

Abstract

2/2021 vol. 72
Case report

Bean’s syndrome (blue rubber bleb nevus syndrome – BRBNS) as a gastrointestinal bleeding – case report and review of the literature

  1. Department of Gastroenterology, Hepatology and Clinical Oncology, Centre of Medical Postgraduate Education, Warsaw, Poland
  2. Department of Pathomorphology, Centre of Medical Postgraduate Education, Warsaw, Poland
Pol J Pathol 2021; 72 (2): 190-194
Online publish date: 2021/09/30
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BRBNS is a rare syndrome of vascular malformations caused by the TEK mutation associated with numerous lesions of the skin and gastrointestinal tract. We present a case report of 41 year old man with severe anemia with recurrent bleedings. The detailed clinical, endoscopical and histopathological description is given as a wide range of differential diagnosis of vascular lesions based on pathophysiology and updated classification of vascular lesions. Clinicopathological diagnosis and treatment options of BRBNS are discussed.
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