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Original paper

Bilateral translaminar osseous-channel assisted percutaneous full-endoscopic ligamentectomy decompression for thoracic myelopathy due to ossification of the ligamentum flavum: a technical note

Zhijun Xin
Weijun Kong
Qian Du
Wenbo Liao

Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China
Videosurgery Miniinv
Online publish date: 2020/11/15
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Ossification of the ligamentum flavum (OLF) is a well-known cause of thoracic spinal stenosis that has been identified as the primary cause of thoracic myelopathy (TM) [1–3]. Particularly in East Asian regions, the incidence of thoracic OLF can be as high as 36% in the Japanese population and 63.9% in the Chinese population, although most such cases do not necessarily develop into asymptomatic thoracic canal stenosis and TM [4]. Once the thoracic OLF is symptomatic, surgical intervention is recommended because it is refractory to conservative treatment [5, 6], and this approach also avoids acute myelopathy induced by a minor trauma [7]. Although several multiple decompression procedures with open approaches or tube techniques, including laminectomy [2], aminoplasty [8], with or without instrumented fusion [6], have been described, the optimal surgical procedure remains controversial [1, 7], and surgical outcomes are not always satisfactory [2, 9]. The major concerns include greater iatrogenic trauma [10], a higher risk of neurological deterioration and complications [5, 11], and whether instrumentation should be used after the decompression procedure [6, 12]. With the advancement of surgical techniques and instruments, good results and advantages have been described for full-endoscopic discectomy techniques for lumbar stenoses and cervical spondylosis myelopathy [13–15]. However, few reports have explored the use of posterior percutaneous full-endoscopic ligamentectomy decompression (p-PELD) for TM caused by OLF.


The objective of this study was to describe the rationale, surgical technique, and the results of a new minimally invasive spinal surgery (MISS) technique, bilateral translaminar osseous-channel assisted posterior p-PELD, as a treatment for TM caused by OLF.

Material and methods


Additional informed consent was obtained from a 51-year female patient who was transferred to our hospital from a regional hospital after a percutaneous vertebroplasty (PVP) with methyl methacrylate inserted for T11 osteoporotic compression fracture (OCF). Prior to hospitalization, with denial of a traceable history of trauma, a 2-year history of progressive thoracolumbar back pain and numbness disturbance of the lower limbs was present. Progressive spastic paraparesis of the lower extremity was present for 3 months, and gait disturbance with bladder and bowel sphincter dysfunction was present for 2 weeks. A physical examination revealed hypoalgesia in the bilateral lower extremities and inguinal regions. In addition, diffuse weakness was observed in the bilateral lower extremities, with 4/5 strength reported in all muscle groups. With a bilateral positive Babinski sign, her patellar tendon reflex and Achilles’ tendons reflex were also exaggerated. Even with no symptomatic deterioration on the fifth day after the initial PVP operation, there were still 6 points of thoracolumbar back pain residue according to a visual analogue scale (VAS) evaluation [16], and her score in the modified Japanese Orthopaedic Association (mJOA) scoring system (Table I) for TM was 2 out of 11 possible points [17]. Preoperative diagnostic imaging included plain radiography, computed tomography (CT), and magnetic resonance imaging (MRI), which were performed before the initial PVP operation. However, no postoperative control CT was performed between the vertebroplasty and the endoscopy. No evidence of instability was found on flexion and extension lateral radiographs. A CT scan demonstrated spinal canal stenosis at the T10/11 level due to the presence of OLF (Photo 1). An MRI revealed dorsal compression and myelomalacic changes of the spinal cord at the T10/11 level secondary to OLF (Photo 2).

Surgical technique and intraoperative findings

After a diagnosis of TM caused by OLF was made, bilateral translaminar osseous-channel assisted p-PELD for resection of the OLF was performed at the T10/11 level. After general anaesthesia and neurological monitoring were performed, the patient was placed in a prone position. Intraoperative radiography was used to confirm the involved segment, and the surface projection of the responsible OLF was marked on the skin with ink. A needle was inserted with a trajectory aimed at the laminar target position (beginning with the right side) where the OLF lay hidden under the monitor of a “C” arm X-ray machine. Then, a 6-mm dilator was inserted along the guide needle onto the laminar target position to bluntly separate the muscles. Insertion of a trephine (OD = 7.5 mm, ID = 6.5 mm, Joimax, Germany) was performed via the dilator, and punching was performed on the target position of the lamina. Then, we performed a clockwise rotation and forwarding accuracy depth (Photos 3 A, B), which was measured using preoperative imaging of the vertebral lamina. Then, the exact resected area of the lamina was removed overall with the trephine (Photo 3 C), and a translaminar osseous channel was made to allow the working sheath access into the canal (Photos 3 D, E).
Then, the endoscope was inserted through the working sheath, and the further operation was performed under visual control and continuous irrigation with 0.9% saline solution. Limited laminectomy and adequate resection of the OLF was performed using a 3-mm diameter endoscopic high-speed drill (Midas Rex; Medtronic, Fort Worth, Texas, Germany) under endoscopic visualization (Photo 4 A). In this procedure, decompression was performed only on the side ipsilateral to the ossification lesion by slightly tilting the working sheath in combination with a 30-degree endoscope to achieve accurate, adequate decompression of the target area (Photo 4 B). Care was taken to reduce direct extrusion on the dural sac during the decompression process.
Full exposure to the lateral margin and medial part of the dural sac was applied to achieve sufficient decompression, and free-floating dura mater in the irrigation fluid was considered a sign of sufficient decompression. After adequate decompression was confirmed, a meticulous close suture of the soft tissue was performed without the use of drainage. Then, the same operation was performed on the left side. There was no specific postoperative management. After bed rest for 1 day after surgery, the patient was discharged from the hospital on the third postoperative day and required to ambulate with assistance by a thoracolumbar orthotic brace for the next 3 months. Surgery-related indicators were collected, and radiological and clinical evaluations were performed preoperatively and at 1 week, 3 months, and 2 years postoperatively.


After bilateral decompression at a single segment of the thoracic spine was successfully performed in this patient, her clinical symptoms improved, and she began to walk with the assistance of a unilateral crutch on the second postoperative day. The operation time was 109 min for the bilateral decompression, and there was little bleeding, which was estimated to be about 20 ml. During a 2-year follow-up period, no complications were observed in the patient. No evidence of instability or hypermobility was found at the T10/11 level on postoperative lateral dynamic radiographs (Photo 5), and adequate resection of the OLF and decompression of the spinal cord were observed on postoperative CT (Photo 6) and MRI (Photo 7).
The numbness of the bilateral lower extremity and inguinal regions was improved immediately after the operation, and the muscle strength of the lower extremities and sphincter continued to improve further with the passage of time. Generally, the patient’s clinical outcome was good, including the VAS for thoracolumbar back pain that improved from preoperative 6, to 3, 1, and 0 at 1 week, 6 months, and 2 years postoperatively, respectively, and the mJOA score for neurological status, which improved from preoperative 2 to 4, 7, and 10 at one week, 6 months, and 2 years postoperatively, respectively (Table II).


As one of the primary causes of thoracic spinal stenosis and TM [1, 18], OLF has been shown to have a prevalence of 3.8% to 25% in previous studies [19, 20]. With the improvement of diagnostic techniques and the increasing use of CT scanning and MRI, higher prevalence rates of OLF have been confirmed, including a rate as high as 63.9% in Chinese populations [21]. Although the pathological mechanism of OLF remains unclear, many conceivable risk factors have been proposed, such as mechanical, degenerative, metabolic, genetic, and dietary factors [22, 23]. However, there is still no effective way to prevent or reduce the incidence of this disease. The most commonly involved segments are located at the lower thoracic spine [7], especially the T10-12 level [22, 24]. Multiple symptoms, including radicular and/or myelopathic symptoms, may occur [25, 26].
Due to the progressive nature of OLF and the finding that it is refractory to conservative treatment, surgical intervention is recommended once neurological symptoms are present [5, 27]. On the other hand, surgery is also facilitated to avoid the occurrence of irreversible damage to the spinal cord after minor trauma, which has a pathological basis in the thoracic spinal stenosis caused by OLF [7, 28]. With the goal of developing a surgical intervention able to remove the pathological lesion and to achieve sufficient decompression of the neural structures [7, 29, 30], various surgical techniques have been explored, including posterior and non-posterior approaches through open or non-open methods. Because the neurological deficits are due to the dorsal compression of the spinal cord secondary to OLF [29], most surgeons advocate the use of posterior decompression methods, which include laminectomy [2, 8], laminotomy [20], and laminoplasty [10], as more appropriate for the treatment of thoracic OLF.
Although various surgical procedures have been reported to be effective for OLF in the literature, the optimal surgical approach has not yet been determined [4, 17], and surgical outcomes are not always satisfactory [9, 28]. The reported mean neurological recovery rate after decompression surgery has varied from 31% to 68% in the literature [29, 31], the incidence of neurological deterioration after surgery is reported to be as high as 14.5% to 33% [32, 33]. and the overall complication rate reported in the literature ranges from 35% to 51% [7, 33]. Many scholars consider that one of the reasons for the poor results achieved after decompression surgery is severe iatrogenic injury of the posterior column stable structure, which is related to delayed kyphosis and causes late neurological deterioration [28, 29, 34]. In addition, preservation of the posterior column stable structure is necessary to avoid internal instrumentation and concomitant fusion [10, 35]. To achieve a satisfactory result in decompression surgery while minimizing iatrogenic damage to the spinal stabilizing structures, a minimally invasive and effective surgical technique is warranted [28, 34]. In recent years, the microendoscopic discectomy (MED) technique, combined with the use of a tubular retractor system, has been explored for the treatment of thoracic OLF [3, 34, 36]. As reported in previous studies [3, 34], the mean recovery rate after MED ranges from 49.10% to 44.9%. Even though good clinical results have been reported with this procedure, there is still a risk concomitant with delayed kyphosis [36], and some authors have stopped performing this procedure because of technical difficulties [36, 37].
Superior to the MED technique, a percutaneous spinal endoscopic procedure is widely applied in cervical and lumbar spine disorders to achieve excellent surgical visualization [15], an enlarged visual field due to the use of optical instruments, less iatrogenic trauma, and a faster postoperative recovery process. With growth of experience among spinal surgeons, improvement in surgical instruments, and the ability to achieve adequate bone and soft tissue resection, the scope of indications for the percutaneous spinal endoscopic technique has expanded [38, 39]. However, few papers have reported the use of percutaneous endoscopic ligamentectomy decompression for TM caused by OLF. Based on our proficiency in percutaneous endoscopic discectomy for cervical and lumbar spine disorders, an attempt was made to use the percutaneous endoscopic technique to treat TM caused by OLF.
In this case, an osseous channel is created in the bilateral lamina to precisely assist p-PELD of the lesion, and the rim of the lamina is left intact both superiorly and inferiorly. During its course, the spinous process, supraspinal ligaments, interspinous ligament and lateral part of the facet joints are preserved, which is important to prevent postoperative segmental instability and delayed kyphosis. Therefore, this procedure achieves satisfactory clinical results through adequate decompression and avoids the economic burden caused by the need for additional internal fixation and fusion. For this patient, who had been treated with a PVP for the inferior vertebral body adjacent to the involved segment, the p-PELD procedure was more appropriate, and no postoperative segmental instability or kyphosis was noted at the 2-year follow-up. Another rationale for using the p-PELD technique for treating thoracic OLF is its excellent ability to provide illumination and visualization of a 30° angle field, which was used to obtain an enlarged view of the lesions and a sufficiently wide working area to deal with the lesions.
Our technique is different from the interlaminar endoscopic discectomy technique that was reported by Ruetten and Miao [12, 40]. Although they also used spinal endoscopy to decompress the OLF-related TM, there are many differences between their technique and our bilateral translaminar osseous-channel assist p-PELD technique. First, we used translaminar osseous-channel decompression rather than laminoplasty to preserve the intact rim of the lamina both superiorly and inferiorly, and that will provide more stability and postoperative self-healing for the translaminar osseous tunnel. Second, under the guidance of intraoperative C-arm X-rays, we used a trephine instead of a high-speed drill to punch through the lamina and establish an osseous channel to assist p-PELD, which provides more security for avoiding the frequent stimulation of high-speed drill buffeting and greater efficiency for the overall removal of the laminar excision; furthermore, the entire duration of the operative procedure for bilateral decompression was 109 min. Third, we performed ipsilateral decompression with a bilateral approach rather than bilateral decompression with a uniportal approach because accurate and direct ipsilateral decompression provides greater security and efficiency. After all, the spinal canal in the thoracic region is so narrow that there is very little room for operating [29], and inserting even a fine hook or 1-mm rongeur into the stenotic thoracic canal may cause irreversible neurological deterioration [2].
Although a satisfactory clinical outcome was achieved in this patient with no serious complications after the p-PELD technique was performed, there are some potential disadvantages of this minimally invasive procedure. We believe that the major disadvantage of the p-PELD procedures is its steep learning curve due to the angled field of two-dimensional visualization and the difficulty of hand-eye coordination. However, those can be overcome by emphasizing training in p-PELD procedures in the lumbar spine. In addition, to reduce the risk of neurological deterioration and improve the safety of surgery, many technical tips for this p-PELD procedure should be noted. One technical tip is to exactly pierce the inner cortex of the lamina by gently and repeatedly rotating the trephine to facilitate the overall removal of the laminar excision. Particular attention should be paid to the trephine, which can be monitored on the intraoperative X-ray to ensure that the inner cortex is penetrated without any violence to the spinal cord, which may cause irreversible neurological deterioration. Another technical tip is to drill the thickest part of the OLF so that it is paper thin, especially in its central part, to avoid detachment and floating of the OLF fragment, which is difficult to fix and is not conducive to subsequent buffing. Subsequently, the periphery of the OLF is drilled so that the paper-thin OLF remains intact to protect the spinal cord from damage. Then, we cautiously dissected and removed the paper-thin OLF fragment away from the dura. In addition, a blunt hook was used to find the medial edges of the pedicles to define the range required for bone resection while remaining conscious that the articular process or laminar debridement should not be less than 50% so as not to affect spinal stability and thereby minimize the risk of spinal instability or kyphotic deformity caused by the excessive bone resection during the procedure [24]. In this case, the p-PELD procedure achieved satisfactory clinical results with many advantages, such as less iatrogenic invasiveness, excellent illumination and visualization, a reduced economic burden and higher safety. Each procedure has its own indications, including whether it is a minimally invasive procedure or not. As an accurate and controlled decompression technique, this p-PELD procedure is more adapted for localized and isolated lesions than extensive and continual lesions. Therefore, it is more appropriate in patients with single-level OLF-related TM. Cerebrospinal fluid leakage (CFL) is the main complication after thoracic OLF surgery reported in the literature [11]. It was not noted in this case. We speculate that there was no dural ossification in this patient.
We would like to highlight that there are limitations of this study. Only 1 patient was included in the study, limiting our interpretation of the results. Another limitation is that the patient who was included did not have dural ossification, which reduces the difficulty of the p-PELD procedures. Consequently, a larger case study is warranted to verify the efficacy and safety of this p-PELD technique in the treatment of OLF-related TM.


In this case, we used a novel minimally invasive technique, bilateral translaminar osseous-channel assisted p-PELD for the treatment of OLF-related TM, and satisfactory results were obtained. Theoretically, the p-PELD technique has many advantages, such as less iatrogenic trauma, excellent illumination and visualization, a particular operating field, and no need for internal fixation; furthermore, it is technically feasible for the treatment of single-level and isolated OLF-related TM. Definitive therapeutic effects and safety still need to be demonstrated in a larger sample clinical study, but this p-PELD technique should be considered as an optional treatment for OLF-related TM due to its potential indications and advantages.


We thank Fujun Wu, Xing Chen, Hao Yuan, and Jin Li for the preparation of illustrations.

Conflict of interest

The authors declare no conflict of interest.
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