eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
2/2022
vol. 39
 
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abstract:
Letter to the Editor

Blueberry muffin baby syndrome. A critical primary sign of systemic disease

Katarzyna Kaleta
1
,
Agata Kłosowicz
1
,
Natalia Juśko
1
,
Monika Kapińska-Mrowiecka
1

1.
Department of Dermatology and Venereology, Stefan Zeromski Municipal Hospital, Krakow, Poland
Adv Dermatol Allergol 2022; XXXIX (2): 418-420
Online publish date: 2022/05/09
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Blueberry muffin baby syndrome is a rare and non-specific clinical presentation in newborns, characterized by the presence of widespread, maculopapular lesions of blue-red or violaceous colour and cohesive consistency [1]. The term “blueberry muffin baby” was initially coined to describe the skin manifestations of congenital rubella during the American epidemic in the 1960s [2, 3]. The presence of skin lesions is secondary to extramedullary hematopoiesis, which can result from intrauterine viral infections (TORCH syndrome), hematologic dyscrasias (twin-to-twin transfusion syndrome, hereditary spherocytosis, haemolytic disease of the newborn) or neoplasms (mastocytosis, histiocytosis, neuroblastoma, rhabdomyosarcoma, leukaemia) [1, 3].
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