Advances in Dermatology and Allergology
eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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1/2026
vol. 43
 
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Original paper

Brachytherapy: an effective and safe treatment for skin cancer: evaluation of a large patient cohort in real-world clinical practice

Kamila Czerw
1, 2
,
Agnieszka Siedlaczek
3
,
Weronika Radecka
4
,
Barbara Radecka
1, 2

  1. Department of Oncology, Institute of Medical Sciences, University of Opole, Poland
  2. Tadeusz Koszarowski Cancer Center, Opole, Poland
  3. Faculty of Mathematics, Physics and Computer Science, University of Opole, Poland
  4. Department of Anatomy, Institute of Medical Sciences, University of Opole, Poland
Adv Dermatol Allergol 2026; XLIII (1): 38-43
DOI: https://doi.org/10.5114/ada.2026.159142
Online publish date: 2026/03/01
Article file
- Brachytherapy.pdf  [0.19 MB]
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1. Polskie Towarzystwo Onkologii Klinicznej (PTOK). Postêpowanie diagnostyczno-terapeutyczne u chorych na raki skóry – zalecenia ekspertów. Oncol Clin Pract 2022. Accessed July 8, 2025. http://onkologia.zalecenia.med.pl/pdf/zalecenia_PTOK_tom1_21_Raki_skory_20211110.pdf
2. Badash I, Shauly O, Lui CG, et al. Nonmelanoma facial skin cancer: a review of diagnostic strategies, surgical treatment, and reconstructive techniques. Clin Med Insights Ear Nose Throat 2019; 12: 1179550619865278.
3. Mendez BM, Thornton JF. Current basal and squamous cell skin cancer management. Plast Reconstr Surg 2018; 142: 373e-87e.
4. Narodowy Instytut Onkologii. Wytyczne postêpowania diagnostyczno-terapeutycznego u chorych na raka skóry. Version 2. November 2024. Accessed July 20, 2025. https://nio.gov.pl/wp-content/uploads/2025/01/Wytyczne-raki-skory_aktualizacja_31.12.2024r_v2.pdf
5. National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Basal Cell Skin Cancer. Version 2.2022. Accessed July 20, 2025. https://www.nccn.org
6. Delishaj D, Rembielak A, Manfredi B, et al. Non-melanoma skin cancer treated with high-dose-rate brachytherapy: a review of literature. J Contemp Brachyther 2016; 8: 533-40.
7. Benkhaled S, Van Gestel D, Gomes da Silveira Cauduro C, et al. The state of the art of radiotherapy for non-melanoma skin cancer: a review of the literature. Front Med 2022; 9: 913269.
8. Guinot JL, Rembielak A, Perez-Calatayud J, et al. GEC-ESTRO ACROP recommendations in skin brachytherapy. Radiother Oncol 2018; 126: 377-85.
9. Likhacheva A, Mussadiq A, Barker CA, et al. Definitive and postoperative radiation therapy for basal and squamous cell cancers of the skin: executive summary of the American Society for Radiation Oncology clinical practice guideline. Pract Radiat Oncol 2020; 10: 8-20.
10. Amin MB, Greene FL, Edge SB, et al. The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin 2017; 67: 93-9.
11. Didkowska J, Wojciechowska U, Barañska K. Nowotwory z³oœliwe w Polsce w 2021 r. Warszawa: Krajowy Rejestr Nowotworów, Narodowy Instytut Onkologii.
12. Borzêcka-Sapko A, Siermontowski P, Mleczko M, et al. Epidemiology of basal cell carcinoma – observations of one department. Pol Hyp Res 2020; 71: 55-66.
13. Chiche³ A, Chyrek AJ, Kluska A, et al. Advanced non-melanoma skin cancer in elderly patients: when surgery says NO, interventional radiotherapy (brachytherapy) says YES. J Contemp Brachythe 2023; 15: 235-44.
14. Krzysztofiak T, Kamiñska-Winciorek G, Pilœniak A, et al. High dose rate brachytherapy in nonmelanoma skin cancer-systematic review. Dermatol Ther 2022; 35: e15675.
15. Taggar AS, Mann P, Stewart A, et al. Acute and late complications and toxicities of skin brachytherapy. Brachytherapy 2021; 20: 1041-52.
16. Zaorsky NG, Lee CT, Zhang E, et al. Skin CanceR Brachytherapy vs External beam radiation therapy (SCRiBE) meta-analysis. Radiother Oncol 2018; 126: 386-93.
17. Lee CT, Lehrer EJ, Aphale A, et al. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: an international meta-analysis of 58 studies with 21,000 patients. Cancer 2019; 125: 3582-94.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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