COVID-19 in two patients with multiple sclerosis treated with beta interferons

Karolina Kania; Elżbieta Tokarz-Kupczyk; Alicja Kalinowska-Łyszczarz

eISSN: 2449-9315
ISSN: 1234-8279

Pharmacotherapy in Psychiatry and Neurology/Farmakoterapia w Psychiatrii i Neurologii

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4/2020
vol. 36

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abstract:

Case report

COVID-19 in two patients with multiple sclerosis treated with beta interferons

Karolina Kania

¹

,

Elżbieta Tokarz-Kupczyk

¹

,

Alicja Kalinowska-Łyszczarz

²

Poznan University of Medical Sciences, Department of Neurology

Poznan University of Medical Sciences, Department of Neurology, Division of Neurochemistry and Neuropathology

Farmakoterapia w Psychiatrii i Neurologii 2020, 36 (4), 327–334

Online publish date: 2021/12/06

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Objectives
Treatment of multiple sclerosis (MS) in the era of the COVID-19 (coronavirus disease 2019) pandemic raises many questions for doctors.

Case reports
We are presenting two cases of patients suffering from multiple sclerosis (MS) treated with interferon beta-1b and interferon beta-1a, who suffered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, with a benign course in one case and an asymptomatic one in another. None of the patients required hospitalisation.

Conclusions
MS treatment during coronavirus disease 2019 (COVID-19) pandemics poses several questions. Considering our own clinical experiences, we present a brief review of medical literature on the safety of MS immunotherapy. So far, the published data on MS and COVID-19 do not show increased risk associated with MS diagnosis or disease modifying therapy, even when associated with immunosuppression.

keywords:

COVID-19 in two patients with multiple sclerosis treated with beta interferons

Karolina Kania 1 , Elżbieta Tokarz-Kupczyk 1 , Alicja Kalinowska-Łyszczarz 2

multiple sclerosis, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19), beta-interferons

Karolina Kania

¹

,

Elżbieta Tokarz-Kupczyk

¹

,

Alicja Kalinowska-Łyszczarz

²