eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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1/2019
vol. 44
 
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abstract:
Case report

Carbamazepine-induced DRESS syndrome leading to reversible myocarditis in a child

Mecnun Çetin
1
,
Mevsim Demir Mis
1
,
Kamuran Karaman
1
,
Íbrahim H. Yavuz
1
,
Hadi Geylan
1
,
Perihan Tunçdemir
1
,
Feyza Demir
1

1.
Yüzüncü Yil University, Turkey
(Centr Eur J Immunol 2019; 44 (1): 102-105)
DOI: https://doi.org/10.5114/ceji.2019.83700
Online publish date: 2019/03/19
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DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome is a rare type of delayed drug hypersensitivity reaction characterised by fever, skin rash, lymphadenopathy, and visceral involvement, which can be life threatening and is a childhood event. An eight-year-old boy was admitted with complaints of extensive rash and fever three weeks after the onset of treatment with carbamazepine for a diagnosis of epilepsy. Fever, as well as patches and plaques with indeterminate limits that tended to merge and were non-blanchable on a widespread erythematous layer, were revealed in physical exami­nation. Extensive cervical, submandibular, and inguinal lymphadenopathy was observed. We present ours as the second case of myocarditis secondary to DRESS syndrome after carbamazepine use in the literature.
keywords:

carbamazepine, DRESS syndrome, lymphadenopathy, myocarditis

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