eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
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3/2007
vol. 3
 
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abstract:

Case report
Episodes of severe menorrhagia at menarche in a girl with von Willebrand disease

Athanasios Christoforidis
,
Marina Economou
,
Miranda Athanassiou-Metaxa

Arch Med Sci 2007; 3, 3: 281-283
Online publish date: 2007/10/01
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We describe a case of a 14-year-old girl with von Willebrand disease (vWD) and episodes of severe menorrhagia at menarche, necessitating hospitalization and requiring blood transfusions and administration of purified von Willebrand factor. Further episodes of menorrhagia were successfully prevented with the use of oral contraceptives and uterine bleeding at menses was regulated with the combination of nasal desmopressin and tranexamic acid per os.
keywords:

von Willebrand disease, menorrhagia, menarche, contraceptive therapy, case report

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