eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
3/2014
vol. 65
 
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abstract:

Case report
High-grade urothelial carcinoma, plasmacytoid variant, of the renal pelvis with osteoclast-like giant cells and focal rhabdoid features

Naoto Kuroda
,
Takushi Naroda
,
Masato Tamura
,
Delia Perez-Montiel
,
Michal Michal
,
Ondrej Hes

Pol J Pathol 2014; 65 (3): 237-240
Online publish date: 2014/10/18
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In this article, we present a rare case of renal pelvic carcinoma. The imaging examination of a 75-year-old Japanese man disclosed the left renal pelvic tumor. The histological examination showed the finding of predominant undifferentiated discohesive mononuclear cells with abundant osteoclast-like giant cells and a minor component of papillary urothelial carcinoma. Rhabdoid morphology was focally seen. Immunohistochemically, mononuclear cells were focally positive for thrombomodulin and showed a high MIB-1 index, whereas osteoclast-like giant cells were positive for CD68. Urologists should bear in mind that a rare association of high-grade urothelial carcinoma, plasmacytoid variant, with osteoclast-like giant cells and focal rhabdoid features may occur in the renal pelvis.
keywords:

renal pelvis, urothelial carcinoma, plasmacytoid, rhabdoid, osteoclast-like giant cells

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