eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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6/2007
vol. 45
 
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abstract:

Case report
Oesophageal manifestations of Churg-Strauss syndrome – case report

Valentyna Chopyak
,
Khrystyna Lishchuk-Yakymovych
,
Halyna Potomkina
,
Mariya Synenka
,
Omelyan Synenky
,
Roman Pukalyak

Reumatologia 2007; 45, 6: 428–430
Online publish date: 2007/12/20
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Churg-Strauss syndrome (CSS) is characterized by asthma, eosinophilia and systemic small and medium-sized vasculitis. We have observed a 34-year old man with a history of asthma suffering from fever, dyspnoea, cough, epigastric burning, epigastric pain and confluent eruption on the skin of the shanks. We diagnosed pulmonary infiltrates (X-ray film of chest). There were found in histological examination of material after oesophageal biopsy mastocytes, lymphocytes and eosinophils (>22 eos/1 high power field). We observed eosinophilia (4.8 G/L), increased serum C-reactive protein and IgE, IL-4, IL-5 and TNF-α concentration in the patient. pANCA were found in the serum of the patient. We diagnosed CSS with oesophageal involvement.
keywords:

Churg-Strauss syndrome, eosinophilia, vasculitis, eosinophilic esophagitis



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