eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
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2/2010
vol. 6
 
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abstract:

Case report
Simultaneous human herpesvirus 6-associated encephalitis and Guillain-Barré syndrome in a patient after matched unrelated donor haematopoietic stem cell transplantation

Agnieszka Tomaszewska
,
Barbara Nasilowska-Adamska
,
Tomasz Dzieciatkowski
,
Bozena Marianska

Arch Med Sci 2010; 6, 2: 288-290
Online publish date: 2010/04/30
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Viral infections are still a serious diagnostic and therapeutic problem in patients undergoing alternative donor transplants. β-Herpesviruses (especially human herpesvirus type 5, 6 and 7) are recognized pathogens in this group of patients and may cause central nervous system disease. Guillain-Barré syndrome (GBS) is a very rare complication among stem cell transplant recipients and usually has been attributed to infection. We report a case of resolving simultaneous GBS and HHV-6-associated encephalitis in a haematopoietic stem cell transplant recipient with preceding reactivation of cytomegalovirus (CMV) infection. According to our knowledge this well-documented case is probably the first report from Poland.
keywords:

human herpesvirus-6, encephalitis, Guillain-Barré syndrome, haematopoietic stem cell transplant recipients

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