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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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SCImago Journal & Country Rank
1/2019
vol. 121
 
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abstract:
Original paper

Clinical and histopathological evaluation of 312 excised conjunctival tumors

Magdalena Dębicka-Kumela
1, 2
,
Izabella Karska-Basta
1, 2
,
Anna Markiewicz
1, 2
,
Anna Bogdali
1, 2
,
Joanna Kowal
1, 2
,
Bożena Romanowska-Dixon
1, 2

1.
Klinika Okulistyki i Onkologii Okulistycznej Katedry Okulistyki Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie Kierownik: prof. dr hab. n. med. Bożena Romanowska-Dixon
2.
Oddział Kliniczny Okulistyki i Onkologii Okulistycznej Szpitala Uniwersyteckiego w Krakowie Kierownik: prof. dr hab. n. med. Bożena Romanowska-Dixon
Online publish date: 2019/06/05
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Aim
Clinical and histological evaluation of conjunctival lesions treated surgically over 1 year in our centre

Material and methods
Retrospective clinical and histological analysis of 312 conjunctival tumors surgically removed at the Department of Ophthalmology, Jagiellonian University in Krakow 2017. The lesions were unilateral in 298 (97.7%) patients and bilateral in 7 (2.3%) patients. The cohort consisted of 164 men and 141 women, aged 1 to 92 years (mean age of 47.9 years).

Results
Histological analysis confirmed benign lesions in 219 (70.2%) cases, malignant lesions in 61 (19.6%) cases and premalignant lesions in 32 (10.2%) cases. The most common pathology was nevus (138 cases, 44.2%), followed by primary acquired melanosis (PAM) without atypia (25 cases, 8%), melanoma (22 cases, 7%), MALT lymphoma (25 cases, 8%), PAM with atypia (14 cases, 4.5%) and squamous cell carcinoma (12 cases, 3.8%). The two most common anatomical locations were caruncle (75 cases, 24%) and bulbar conjunctiva (143 cases, 45.8%), both with (70 cases, 22.4%) and without (73 cases, 23.4%) corneal involvement.

Conclusions
Preliminary clinical diagnosis is not always consistent with ultimate histological findings. Although malignant neoplasms of the conjunctiva are significantly less common than the benign ones, they are life-threatening, so a prompt and accurate histological diagnosis is crucial. The age and sex of the patient, tumour location and bilateral occurrence can aid the preliminary diagnosis and clinical decision making about surgery.

keywords:

conjunctiva, conjunctival tumours, conjunctival lesions, nevus, melanoma, lymphoma

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