Postępy Dermatologii i Alergologii

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4/2026 vol. 43
Original paper

Clinical and laboratory characteristics of paediatric patients diagnosed with angioedema: a retrospective evaluation

Halil Alkaya 1
,
Uğur Altaş 1
,
Tuğba Arıkoğlu 2
,
Yakup Söğütlü 3
,
Mehmet Yaşar Özkars 1

  1. Department of Paediatric Allergy and Immunology, Ümraniye Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye

  2. Department of Health Management, Üsküdar University, Istanbul, Türkiye

  3. Department of Paediatric Emergency Medicine, Ümraniye Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye

Adv Dermatol Allergol 2026; XLIII (4): 434-440

DOI: https://doi.org/10.5114/ada.2026.164276
Data publikacji online: 2026/09/14
Article file
PDiA Clinical.pdf
  1. Lewis LM. Angioedema: etiology, pathophysiology, current and emerging therapies. J Emerg Med 2013; 45: 789-96.
  2. Wilkerson RG. Angioedema in the emergency department: an evidence-based review. Emerg Med Pract 2012; 14: 1-21.
  3. Gülbahar O, Gelincik A, Sin A, et al. Herediter anjiyoödem. Asthma Allergy Immunol 2010; 8: 125-38.
  4. Maurer M, Magerl M, Ansotegui I, et al. The international WAO/EAACI guideline for the management of hereditary angioedema: the 2017 revision and update. Allergy 2018; 73: 1575-96.
  5. Jaiganesh T, Wiese M, Hollingsworth J, et al. Acute angioedema: recognition and management in the emergency department. Eur J Emerg Med 2013; 20: 10-7.
  6. Radonjic-Hoesli S, Hofmeier KS, Micaletto S, et al. Urticaria and angioedema: an update on classification and pathogenesis. Clin Rev Allergy Immunol 2018; 54: 88-101.
  7. Depetri F, Tedeschi A, Cugno M. Angioedema and emergency medicine: from pathophysiology to diagnosis and treatment. Eur J Intern Med 2019; 59: 8-13.
  8. Wada A, Sawada Y, Sugino H, et al. Angioedema and fatty acids. Int J Mol Sci 2021; 22: 9000.
  9. Pall AH, Lomholt AF, von Buchwald C, et al. Clinical features and disease course of primary angioedema patients in a tertiary care hospital. J Asthma Allergy 2020; 13: 225-36.
  10. Cicardi M, Aberer W, Banerji A, et al. Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group. Allergy 2014; 69: 602-16.
  11. Soyöz O, Harmancı K. Akut ürtiker ve anjioödem tedavisi. Turkiye Klinikleri Pediatr Immunol Allergy-Special Topics 2022; 3: 48-51.
  12. Zuberbier T, Aberer W, Asero R, et al. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Allergy 2018; 73: 1393-414.
  13. Maurer M, Sofen H, Ortiz B, et al. Positive impact of omalizumab on angioedema and quality of life in patients with refractory chronic idiopathic/spontaneous urticaria: analyses according to the presence or absence of angioedema. J Eur Acad Dermatol Venereol 2017; 31: 1056-63.
  14. Bernstein JA, Moellman J. Emerging concepts in the diagnosis and treatment of patients with undifferentiated angioedema. Int J Emerg Med 2012; 5: 39.
  15. Ferrer M, Rodriguez-Garijo N, Sabaté-Brescó M. Medical algorithm: diagnosis and management of histaminergic angioedema. Allergy 2023; 78: 599-602.
  16. Busse PJ, Christiansen SC. Hereditary angioedema. N Engl J Med 2020; 382: 1136-48.
  17. Hişmioğulları A, Sancaklı Ö, Ocak M, et al. Outcomes of oral food challenge in children with IgE-mediated food allergy. Allergol Immunopathol 2026; 54 (Suppl 1): 10-7.
  18. Alkaya H, Altaş U, Çevik S, et al. Evaluation of clinical characteristics of patients with tree nut sensitivity. Alergol Pol 2024; 11: 299-303.
  19. Migliarino V, Zago A, Martelossi C, et al. Natural history of pediatric idiopathic histaminergic angioedema: a retrospective monocentric study. Children 2025; 12: 600.
  20. Sekerel BE, Ilgun Gurel D, Sahiner UM, et al. The many faces of pediatric urticaria. Front Allergy 2023; 4: 1267663.
  21. Sabaté-Brescó M, Rodriguez-Garijo N, Azofra J, et al. A comparative study of sex distribution, autoimmunity, blood, and inflammatory parameters in chronic spontaneous urticaria with angioedema and chronic histaminergic angioedema. J Allergy Clin Immunol Pract 2021; 9: 2284-92.
  22. Bas M, Hoffmann TK, Bier H, et al. Increased C-reactive protein in ACE inhibitor–induced angioedema. Br J Clin Pharmacol 2005; 59: 233-8.
  23. Aydoğdu A, Aydoğdu A. Analysis of the association of allergic disease in pediatric patients with hereditary angioedema. Osmangazi Med J 2023; 45: 321-5.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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