eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
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5/2010
vol. 6
 
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abstract:

Clinical research
Changes in attainment of lipid goals by general practitioners and specialists in patients at high cardiovascular risk in Hungary during 2004-2008

Laszlo Mark
,
György Paragh
,
Istvan Karadi
,
Istvan Reiber
,
Gyula Pados

Arch Med Sci 2010; 6, 5: 695-700
Online publish date: 2010/10/27
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Introduction : Lipid-lowering therapy should achieve target levels. We assessed the change of the achievement of targets and the mean low-density lipoprotein cholesterol (LDL-C) levels in high-risk Hungarian patients.
Material and methods : Six studies performed with patients of general practitioners (GPs) and specialists between 2004 and 2008 were evaluated: 9,508 patients from GPs and 2809 from specialist practices (total 12,317).
Results : During this 4-year period the LDL-C level decreased by 0.73 mmol/l and the LDL-C goal achievement rate increased from 14 to 32% in patients treated by GPs. LDL-C showed a decrease of 0.48 mmol/l and the goal achievement rate changed from 20 to 43% in patients treated by specialists. In the majority of the patients not achieving the LDL-C goal (57% for specialists and 89% for GPs) there was no modification in the current therapy. In addition to emphasizing the priority of LDL-C lowering, we should also strive for residual risk reduction, which means raising high-density lipoprotein cholesterol (HDL-C) and lowering triglyceride levels. There was no significant improvement in HDL-C or triglyceride levels during the examined period.
Conclusion : More attention needs to be paid to changing treatment of patients to achieve target levels.
keywords:

prevention, risk factors, hypercholesterolaemia, statins, LDL cholesterol

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