eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
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3/2010
vol. 6
 
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abstract:

Clinical research
Successes and pitfalls of chronic peritoneal dialysis in infants – a Polish nationwide outcome study

Anna Jander
,
Irena Makulska
,
Joanna Latoszyńska
,
Hanna Boguszewska-Bączkowska
,
Irena Bałasz-Chmielewska
,
Ilona Zagożdżon
,
Iga Załuska-Leśniewska
,
Ewa Stefaniak
,
Beata Leszczyńska
,
Katarzyna Zachwieja
,
Ryszard Wierciński
,
Hanna Kipigroch
,
Barbara Kołłątaj
,
Marcin Tkaczyk

Arch Med Sci 2010; 6, 3: 414-419
Online publish date: 2010/06/30
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Introduction: Peritoneal dialysis (PD) is a preferred method of renal replacement therapy for end-stage renal disease in children. Recent advances have allowed chronic PD to be provided to children of all ages and sizes.
Material and methods: The study was designed as a national (10 dialysis centres), multicentre retrospective analysis of the medical history of 33 children who started chronic peritoneal dialysis in their infancy between 1993 and 2005, with a follow-up period of at least 24 months.
Results: The nutritional status of the infants was unsatisfactory. The mean SDS of body weight at the start was –2.0, at 1 year of age –1.7. Only 40% of infants were adequately nourished at 1 year of age. Long-term follow-up analysis showed that 12 children received a kidney transplant, 13 were still on dialysis (4 changed method) and 6 died (mortality rate in the first year of life of 9%). In 2 children we observed an improvement of renal function. We observed a relatively high (1/8.8 patient-months) peritonitis rate in the analysed children when compared to 1 : 22 patient-months in all children undergoing PD in Poland.
Conclusions: The results of our survey have shown that the management of dialysed infants is still a challenge for the medical team and families, but long-term results of the therapy are encouraging.
keywords:

infant, chronic dialysis, peritoneal dialysis, outcome, children

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