eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
4/2015
vol. 66
 
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abstract:
Original paper

Clinicopathologic analysis of isolated hematuria in child/adolescent and adult patients

GuangLei Chen
,
Jun Zhu
,
MingHui Song
,
Lu Ma
,
Tao Pan
,
Qi Yang
,
WenSheng Zhang

Pol J Pathol 2015; 66 (4): 353-360
Online publish date: 2016/02/05
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To our knowledge, no in-depth clinicopathologic study of isolated hematuria (IH) is currently available. To address this gap, we analyzed the clinicopathologic features of IH as it manifests in child/adolescent and adult patients. The clinical data and pathological types of 543 IH patients who underwent renal pathological examinations from January 2005 to June 2010 were retrospectively analyzed. Clinical manifestations differed among the age groups: children/adolescents exhibited the highest percentage of mesangial proliferative glomerulonephritis (41.78%), whereas adults showed the highest percentage of immunoglobulin A nephropathy (IgAN) (52.39%). In addition, the percentage of IH patients who were classified according to clinical pathology differed from that of patients who were classified according to renal pathological type. Patients with IgAN who were found to have minimal proteinuria had more severe IH. For IH patients, especially those with a small amount of proteinuria, renal biopsy should be performed as early as possible in order to develop a long-term treatment plan and prognosis evaluation.
keywords:

isolated hematuria, clinical, pathology, child, adolescent, adult

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