Polish Journal of Pathology

Abstract

4/2016 vol. 67
Original paper

Comparison of apparent diffusion coefficient in diffusion-weighted magnetic resonance imaging and morphological assessment of breast tumors

Pol J Pathol 2016; 67 (4): 398-403
Online publish date: 2017/02/10
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Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
The aim of the study was to assess the relationship between the apparent diffusion coefficient in diffusion-weighted magnetic (DWM) resonance imaging (MRI) and selected morphological parameters of the breast lesions. Diffusion-weighted imaging data and the pathology reports of 160 women treated surgically between January 2011 and March 2015 were analyzed. When classified, 107 invasive carcinomas, 13 pre-invasive carcinomas and 40 benign lesions were identified. The mean apparent diffusion coefficient was significantly lower for invasive carcinomas than benign lesions of the breast (0.87 ±0.02 vs. 1.58 ±0.04; p < 0.001). What is more there was an inverse correlation between value of apparent diffusion coefficient in diffusion-weighted magnetic resonance imaging and the grade of breast carcinomas (p = 0.04).
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