ISSN: 2544-4395
Physiotherapy Quarterly
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vol. 31
Original paper

Comparison of the effects of a physiotherapy protocol and platelet-rich plasma treatment on pain, functionality, and kinesiophobia in women with medial compartment osteoarthritis of the knee

Fatma Nur Alcin
Begumhan Turhan

Golhisar Vocational School of Health Services, Burdur Mehmet Akif Ersoy University, Burdur, Turkey
Department of Anatomy, Faculty of Medicine, Başkent University, Ankara, Turkey
Physiother Quart. 2023;31(1):39–45
Online publish date: 2023/03/21
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Although the popularity of platelet-rich plasma treatments has recently increased, physiotherapy is still one of the recommended methods of gonarthrosis treatment. The aim of the study was to examine the preferability of lower-cost physiotherapy compared with high-cost platelet-rich plasma treatment for gonarthrosis and the effects of both treatments on pain, functionality, and kinesiophobia.

Overall, 61 women participated in this randomized controlled study. The first group (physiotherapy) received conservative physiotherapy treatment (hot pack, ultrasound, transcutaneous electrical nerve stimulation, manual therapy) and home exercises. The second group (platelet-rich plasma) underwent only a home exercise program. An isometric knee exercise, an isotonic knee exercise, and dynamic step exercises for the quadriceps femoris muscle were planned for the home exercises. Exercise program compliance was monitored by exercise diary and telephone calls every day. The patients were evaluated in terms of pain levels, physical limitations (WOMAC and Lysholm scales), and kinesiophobia (Tampa Scale for Kinesiophobia). Data were collected 4 times (before treatment and in the 4th, 8th, and 12th week).

The patients’ average age was 60.92 ± 10.67 years. In both groups, there was a decrease in pain and WOMAC and Tampa scores, and an increase in Lysholm scores compared with the pre-treatment outcomes (p < 0.05). No between-group difference in these parameters was observed (p > 0.05).

The scarce difference in the indirect comparisons of the groups in terms of pain, functionality, and kinesiophobia scores may indicate that the two treatment methods may be equally recommended.


platelet-rich plasma, physiotherapy, knee joint, gonarthrosis

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