eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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SCImago Journal & Country Rank
 
2/2019
vol. 57
 
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abstract:
Review paper

Determination of antibodies in everyday rheumatological practice

Katarzyna Napiórkowska-Baran
,
Joanna Zalewska
,
Sławomir Jeka
,
Iwona Dankiewicz-Fares
,
Marcin Ziętkiewicz
,
Ewa Szynkiewicz
,
Sylwia Kołtan
,
Adam Wawrzeńczyk
,
Ewa Więsik-Szewczyk
,
Zbigniew Bartuzi

Reumatologia 2019; 57, 2: 91-99
Online publish date: 2019/04/29
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Antibody determination is routinely used in everyday rheumatological practice. Its result repeatedly determines the diagnosis or exclusion of a particular disease. Antibodies are immunoglobulins, i.e. some of the most important proteins in the immune system, and have specific properties that we should know. In addition, there are a number of factors that can affect their concentration, including drugs commonly used in the treatment of rheumatic diseases. There are definite indications, when the total concentrations of individual classes of immunoglobulins should be initially determined and it should be evaluated whether the patient produces them at all or their production is impaired. In some cases, we should evaluate the levels of specific antibodies along with the total protein concentration and the -globulin fraction, in which the antibodies are contained. The article presents information on the most common mistakes made when performing these tests.
keywords:

rheumatic diseases, immunoglobulins, antibodies







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