Folia Neuropathologica

4/2025 vol. 63
Opis przypadku

Diagnostic difficulties in progressive multifocal leukoencephalopathy: a case report

  1. Department of Neurosurgery, Institute of Psychiatry and Neurology, Warsaw, Poland
  2. 2nd Department of Neurology, Institute Psychiatry and Neurology, Warsaw, Poland
  3. Department of Neuropathology, Institute Psychiatry and Neurology, Warsaw, Poland
Folia Neuropathol 2025; 63 (4): 420-425
Data publikacji online: 2025/12/09
Plik artykułu
Diagnostic.pdf
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1. Astrom KE, Mancall EL, Richardson EP. Progressive multifocal leuko-encephalopathy; a hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin’s disease. Brain J Neurol 1958; 81: 93-111.
2. Baldassari LE, Wattjes MP, Cortese ICM, Gass A, Metz I, Yousry T, Reich DS, Richert N. The neuroradiology of progressive multifocal leukoencephalopathy: a clinical trial perspective. Brain 2022; 145: 426-440.
3. Bennett KM, Fernandes PM. Novel treatments for progressive multifocal leukoencephalopathy. Br J Hosp Med 2020; 81: 1-9.
4. Berger JR, Aksamit AJ, Clifford DB, Davis L, Koralnik IJ, Sejvar JJ, Bartt R, Major EO, Nath A. PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology 2013; 80: 1430-1438.
5. Bernard-Valnet R, Koralnik IJ, Du Pasquier R. Advances in treatment of progressive multifocal leukoencephalopathy. Ann Neurol 2021; 90: 865-873.
6. Chiu CY, Amenta E, Chavez V, Fukuta Y, Hasbun R. Undetectable JC virus CSF PCR in patients with JC virus-induced progressive multifocal leukoencephalopathy. J Neurovirol 2023; 29: 94-99.
7. Cortese I, Reich DS, Nath A. Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease. Nat Rev Neurol 2021; 17: 37-51.
8. Kulma-Kreft M, Leśniewski-Kmak K, Zaucha JM. Diagnostyka i leczenie postępującej wieloogniskowej leukoencefalopatii. Acta Haematol Pol 2015; 46: 280-285.
9. Mouliou DS. John Cunningham virus and progressive multifocal leukoencephalopathy: A falsely played diagnosis. Diseases (Basel, Switzerland) 2024; 12: 100.
10. Pavlovic D, Patera AC, Nyberg F, Gerber M, Liu M; Progressive Multifocal Leukeoncephalopathy Consortium. Progressive multifocal leukoencephalopathy: Current treatment options and future perspectives. Ther Adv Neurol Disord 2015; 8: 255-273.
11. Soni N, Ora M, Mangla R, Singh R, Ellika S, Agarwal A, Meyers SP, Girish Bathla. Radiological abnormalities in progressive multifocal leukoencephalopathy: Identifying typical and atypical imaging patterns for early diagnosis and differential considerations. Mult Scler Relat Disord 2023; 77: 104830.
12. Lee SY, Ko HC, Kim SI, Lee YS, Son BC. Progressive multifocal leukoencephalopathy diagnosed by brain biopsy, not by the DNA test for JC virus. Asian J Neurosurg 2019; 14: 240-244.
13. Kitazaki Y, Iwasaki H, Kitai R, Takahashi K, Nakamichi K, Hamano T. Progressive multifocal leukoencephalopathy associated with HIV infection diagnosed by brain biopsy with repeated negative PCR testing of CSF JC virus DNA. Brain Nerve 2020; 72: 541-546.
14. Kano Y, Inoue H, Sakurai K, Yoshida M, Miura Y, Nakamichi K, Saijo M, Yuasa H. Idiopathic CD4-positive lymphocytopenia-associated progressive multifocal leukoencephalopathy confirmed by brain biopsy following negative results of repeated CSF-JC-virus tests: a case report. Rinsho Shinkeigaku 2018; 58: 750-755.
15. Ikeda J, Matsushima A, Ishii W, Goto T, Takahashi K, Nakamichi K, Saijo M, Sekijima Y, Ikeda SI. Brain biopsy is more reliable than the DNA test for JC virus in cerebrospinal fluid for the diagnosis of progressive multifocal leukoencephalopathy. Intern Med (Tokyo, Japan) 2017; 56: 1231-1234.
16. Vulliemoz S, Lurati-Ruiz F, Borruat FX, Delavelle J, Koralnik IJ, Kuntzer T, Bogousslavsky J, Picard F, Landis T, Du Pasquier RA. Favourable outcome of progressive multifocal leucoencephalopathy in two patients with dermatomyositis. J Neurol Neurosurg Psychiatry 2006; 77: 1079-1082.
17. Aksamit AJ. Treatment of non-AIDS progressive multifocal leukoencephalopathy with cytosine arabinoside. J Neurovirol 2001; 7: 386-390.
18. Tubridy N, Wells C, Lewis D, Schon F. Unsuccessful treatment with cidofovir and cytarabine in progressive multifocal leukoencephalopathy associated with dermatomyositis. J R Soc Med 2000; 93: 374-375.
19. Gheuens S, Pierone G, Peeters P, Koralnik IJ. Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression. J Neurol Neurosurg Psychiatry 2010; 81: 247-254.
Copyright: © 2025 Mossakowski Medical Research Centre Polish Academy of Sciences and the Polish Association of Neuropathologists. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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