eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
Current issue Archive About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
 
6/2013
vol. 51
 
Share:
Share:
more
 
 
abstract:
Case report

Diagnostic problems in a patient with pulmonary fibrosis and soft tissue calcifications: scleromyositis

Ewa Walewska
,
Robert Rupiński

Reumatologia 2013; 51, 6: 471–473
Online publish date: 2013/12/24
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Overlap syndromes are a spectrum of disorders with mixed clinical features of different connective tissue diseases, which often make the diagnostic process difficult. The article describes the case of a 57-year-old woman with arthralgia, interstitial lung disease and soft tissue calcifications. Despite the absence of any typical skin lesions, predominant clinical features of pulmonary fibrosis and vascular changes in the nailfold capillaroscopy were strongly suggestive of scleroderma-like syndrome. During the course of the disease, six months later, laboratory tests revealed elevated creatine phosphokinase and electromyography confirmed features of primary muscle damage. Since muscle involvement and soft tissue calcifications might be characteristic for scleromyositis, a cutaneous-muscular biopsy was performed to confirm the diagnosis. We speculate that early development of calcifications in this case could be accelerated by vitamin D deficiency and secondary hyperparathyroidism. Small doses of glucocorticosteroids, azathioprine and supplementation of vitamin D were sufficient to control clinical symptoms of the disease.
keywords:

secondary hyperparathyroidism, scleromyositis, systemic sclerosis without scleroderma, soft tissue calcifications



Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe