Abstract
6/2023
vol. 40
Review paper
Differential diagnostics of food allergy as based on provocation tests and laboratory diagnostic assays
- Department of Basic Nursing, Medical University of Warsaw, Warsaw, Poland
- Department of Biochemistry and Pharmacogenomics, Medical University of Warsaw, Warsaw, Poland
- 2nd Department of Paediatrics, Centre of Postgraduate Medical Education, Warsaw, Poland
- Department of Pediatrics and Allergology, The National Institute of Medicine of the Interior and Administration, Warsaw, Poland
- Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Adv Dermatol Allergol 2023; XL (6): 709-715
Online publish date: 2023/11/07
Due to the scale of the phenomenon, food allergies constitute a significant health problem and significantly impair the quality of life of patients. Differential diagnostics, including skin tests, sIgE detection tests, basophil and mast cell activation tests as well as double-blind placebo-controlled food challenge tests, is the gold standard in the diagnosis of food allergies. Recently, increasing attention has been paid to the potential use of intranasal provocation tests in the diagnosis of food allergies. Allergen dose, protocol standardization, assessment of subjective complaints and objectivization of test results are important factors determining the applicability of provocation tests.
Keywords
food allergy, laboratory diagnostics, double-blind, placebo-controlled, intranasal allergen provocation test
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