ISSN: 2451-0637
Archives of Medical Science - Civilization Diseases
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1/2019
vol. 4
 
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abstract:
Clinical research

Does treatment with sub-lingual allergen-specific immunotherapy reduce adenoid size and improve quality of life among Egyptian children?

Nermine Nabil Nermine
1
,
Mohab Mohamed Shehata
2
,
Yasser Taha Madian
3
,
Mohamed Hussien BadrEldin
3

1.
Microbiology and Immunology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
2.
Department of Otolaryngology, Port Fouad Hospital, Port Fouad, Egypt
3.
Otolaryngology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
Arch Med Sci Civil Dis 2019; 4: e51–e57
Online publish date: 2019/07/18
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Introduction
Adenoidal hypertrophy is a paediatric problem. Adenoidectomy contributes to post-operative complications. Allergic rhinitis is a major health problem. Its prevalence in Egypt and the Middle East is up to 9%. The aim of the present study was to evaluate the effect of sub-lingual immunotherapy on adenoid size and/or quality of life among children suffering from adenoid hypertrophy with allergic rhinitis in Suez Canal University Hospital.

Material and methods
Forty-six children suffering from adenoid hypertrophy and allergic rhinitis were recruited for this purpose. Skin prick test was administered to identify the causative allergen. All patients received sub-lingual immunotherapy. Lateral X-ray, serum total immunoglobulin E, symptoms, and sign score were recorded for all patients before and after the treatment.

Results
The nasal symptoms and adenoidal size of the examined patients were significantly decreased after immunotherapy was applied, and thus there was an improvement in the quality of life among those patients.

Conclusions
It was concluded that sub-lingual immunotherapy was an alternative treatment of adenoidectomy in children with moderate adenoid hypertrophy with allergic rhinitis. Surgical treatment for children who suffer from severe adenoid hypertrophy with allergic rhinitis could not be considered as obligatory because medical treatment has no effect on the size of adenoids nor on quality of life.

keywords:

adenoid hypertrophy, allergic rhinitis, sub-lingual immunotherapy, Egypt

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