Abstract
3/2022
vol. 38
Review paper
Oral immunotherapy in children for the most common food allergy
- Student Research Group of Adult Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Group: Krzysztof Gomułka MD, PhD
- Faculty of Medicine, University of Opole, Opole, Poland Head of the Faculty: Jacek Jóźwiak PhD
- Department of Internal Medicine, Pneumology, and Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Department: Robert Pawłowicz MD, PhD
Medical Studies/Studia Medyczne 2022; 38 (3): 210–220
Online publish date: 2022/09/30
Nowadays, the incidence of food allergies is increasing. While strict allergen avoidance remains the most important therapeutic approach, oral immunotherapy is increasingly being used to desensitize and induce tolerance in children. Oral immunotherapy is a possible treatment for food allergies, which includes the administration of gradually increasing doses of the allergen. While most children can be desensitized, or even gain sustained unresponsiveness, oral immunotherapy involves a high risk of side effects or allergic responses with a need to use epinephrine, and the long-term effectiveness is unknown. In this paper, we summarize recent clinical trials in which oral immunotherapy has been used to treat common food allergies: to cow’s milk, peanuts, and chicken eggs.
Keywords
immunotherapy, allergy, desensitization
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