Introduction:

An undesirable consequence of modern medicine and pharmacology is the occurrence of drug reactions. Drug-induced cutaneous reactions account for approximately 70% of all clinical manifestations of adverse drug effects. This can be attributed to the fact that the skin, a signaling organ, is the largest body organ and exhibits significant metabolic/immunological activity.

Case report:

We present the case of a woman with drug-induced subacute cutaneous lupus erythematosus, primary diagnosed as erythema annulare centrifugum, who was hospitalized in the in the Department of Dermatology.

Conclusions:

Knowing that the prevalence of drug-induced subacute cutaneous lupus erythematosus appears to be considerably higher (70%) than previously estimated (20%), the diagnosis of drug-induced subacute cutaneous lupus erythematosus should also be considered when idiopathic subacute cutaneous lupus erythematosus is suspected, particularly if several therapeutics are utilized in patients older then 60 years.