eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
3/2021
vol. 38
 
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abstract:
Original paper

Effect of injectable equine collagen type I on metabolic activity and apoptosis of gingival fibroblasts

Sylwia Klewin-Steinböck
1
,
Agnieszka Nowak-Terpiłowska
2
,
Zygmunt Adamski
3
,
Katarzyna Grocholewicz
4
,
Marzena Wyganowska-Świątkowska
1

1.
Department of Dental Surgery and Periodontology, Poznan University of Medical Sciences, Poznan, Poland
2.
Department of Biochemistry and Biotechnology, Poznan University of Life Sciences, Poznan, Poland
3.
Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland
4.
Department of Interdisciplinary Dentistry, Pomeranian Medical University, Szczecin, Poland
Adv Dermatol Allergol 2021; XXXVIII (3): 440–445
Online publish date: 2020/04/07
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Collagen as a biomaterial is widely used for tissue regeneration due to various advantages including its biodegradation, biocompatibility, and low allergenicity. Along with aesthetic medicine development, collagen is also used in the injectable form as a tissue biostimulator. The area of our study was collagen’s impact on fibroblast activity and apoptosis. The research showed that atelocollagen decreases metabolic activity of fibroblasts, but also showed an increasing number of living cells after 48 h and 72 h incubation under the influence of collagen.
keywords:

gingival fibroblasts, equine collagen, cytotoxicity, apoptosis

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