eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
5/2021
vol. 38
 
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abstract:
Letter to the Editor

Efficacy of omalizumab in reducing latex allergy

Arianna Aruanno
1
,
Raffaella Chini
1
,
Eleonora Nucera
1

1.
Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
Adv Dermatol Allergol 2021; XXXVIII (5): 921-923
Online publish date: 2021/11/05
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Omalizumab, a humanized monoclonal antibody that binds the CH3 domain near the binding site for the high affinity type-I IgE Fc receptors of human IgE, can neutralize free IgE and inhibit the IgE allergic pathway [1].

The current indications for treatment with omalizumab are limited to severe persistent allergic asthma and chronic spontaneous urticaria (CSU) when it is not controlled by conventional anti-H1 treatment at the maximum dosage.

In recent years, several studies [1] have shown that omalizumab is effective in a large number of IgE-mediated and non-IgE-mediated disorders, indicating that omalizumab treatment acts on many levels and not only on immunoglobulins E [2].
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