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ISSN: 1233-9687
Polish Journal of Pathology
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3/2012
vol. 63
 
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abstract:

Epithelioid angiosarcoma metastases to the bone marrow manifesting as erythroblastic anemia and leukocytosis: a case report and review of the literature

Piotr Czapiewski
,
Krzysztof Ważny
,
Ewa Lewicka-Nowak
,
Wojciech Biernat

Pol J Pathol 2012; 3: 199-203
DOI: https://doi.org/10.5114/pjp.2012.31506
Online publish date: 2012/11/09
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Bone marrow is an exceptionally uncommon site of metastatic dissemination in angiosarcoma (AS) as only single case reports have been published so far. We report a case of a 72-year-old male with epithelioid angiosarcoma of the liver who subsequently developed erythroblastic anemia. The trephine bone marrow biopsy revealed total replacement of the normal hematopoiesis by diffuse infiltrate of AS. This rare complication of the clinical course of this tumor should be taken into account in the pathological diagnosis of patients with AS presenting with hematological abnormalities.
keywords:

bone marrow biopsy, metastasis, angiosarcoma
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