Ta strona używa pliki cookies, w celu polepszenia użyteczności i funkcjonalności oraz w celach statystycznych. Dowiedz się więcej w Polityce prywatności.
Korzystając ze strony wyrażasz zgodę na używanie plików cookies, zgodnie z aktualnymi ustawieniami przeglądarki.
Akceptuję wykorzystanie plików cookies
Polish Journal of Pathology
eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
1/2025
vol. 76
 
Share:
Share:
Original paper

Expression of C-terminal tensin-like in breast carcinoma and its correlation with known prognostic factors

Usma Arshad
1
,
Syeda Fatima Rizvi
2
,
Shahzada Khalid Sohail
2
,
Samina Qamar
1
,
Rahat Sarfraz
1
,
Maham Akhlaq
1

  1. Department of Pathology, King Edward Medical University Lahore, Pakistan
  2. Department of Pathology, College of Medicine, University of Bisha, Bisha 61922, Saudi Arabia
Pol J Pathol 2025; 76 (1): 10-15
Online publish date: 2025/05/10
Article file
Get citation
 
PlumX metrics:
 
1. Albasri A, Aleskandarany M, Benhasouna A, et al. CTEN (C-terminal tensin-like), a novel oncogene overexpressed in invasive breast carcinoma of poor prognosis. Breast Cancer Res Treat 2011; 126: 47-54.
2. Lu X, Zhou B, Cao M, Shao Q, Pan Y, Zhao T. CTEN inhibits tumor angiogenesis and growth by targeting VEGFA through down-regulation of β-catenin in breast cancer. Technol Cancer Res Treat 2021; 20: 15330338211045506.
3. Samman A, Hanbazazh M, Samargandy S, Al-Maghrabi J. Expression of p16 protein in breast cancer. Pol J Pathol 2024; 75:19-24.
4. Yalçın Ö, Kulduk G. Tumour budding in invasive breast carcinoma of no special type relationship with clinicopathological parameters. Pol J Pathol 2024; 75: 77-82.
5. Hong SY, Shih YP, Li T, Carraway KL, Lo SH. CTEN prolongssignaling by EGFR through reducing its ligandinduced degradation. Cancer Res 2013; 73: 5266-5276.
6. Lüönd F, Tiede S, Christofori G. Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression. Br J Cancer 2021; 125: 164-175.
7. Lo SH. C-terminal tensin-like (CTEN): a promising biomarker and target for cancer. Int J Biochem Cell Biol 2014; 5: 150-154.
8. Alghamdi S, Alkwai S, Ilyas M. The role of C-terminal tensin like (Cten) gene in cancer metastasis. J Biochem Clin Genet 2018; 1: 2-9.
9. Hong SY, Shih YP, Lo A, Lo SH. Identification of subcellular targeting sequences of Cten reveals its role in cell proliferation. Mol Cell Res 2019; 1866: 450-458.
10. Liao YC, Lo SH. Tensins – emerging insights into their do main functions, biological roles and disease relevance. J Cell Sci 2021; 134: jcs254029.
11. Nizioł M, Pryczynicz A. The role of tensins in malignant neoplasms. Arch Med Sci 2023; 19: 1382-1397.
12. Kawiak A. Molecular research and treatment of breast cancer. Int J Mol Sci 2022; 23: 9617.
13. Katz M, Amit I, Citri A, et al. A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Nat Cell Biol 2007; 9: 961-969.
14. Shehzad K, Alam S, Shams MU, Riaz S, Khan HA, Khan RU. Frequency and pathologic features of triple negative breast cancer at a tertiary care hospital in Pakistan. Ann Punjab Med College 2021; 15: 136-138.
15. Sohail SK, Sarfraz R, Imran M, Kamran M, Qamar S. Estrogen and progesterone receptor expression in breast carcinoma and its association with clinicopathological variables among the Pakistani population. Cureus 2020; 12: e9751.
Copyright: © 2025 Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Quick links
© 2025 Termedia Sp. z o.o.
Developed by Bentus.