Familial localized scleroderma with paediatric onset: a review

Ida Yurtsever; Małgorzata Łukomska; Piotr Sobolewski; Elżbieta Szymańska; Witold Owczarek; Irena Walecka

doi:10.5114/ada.2021.106195

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

Familial localized scleroderma with paediatric onset: a review

Ida Yurtsever

¹

,

Małgorzata Łukomska

¹

,

Piotr Sobolewski

²

,

Elżbieta Szymańska

²

,

Witold Owczarek

³

,

Irena Walecka

²

Department of Dermatology, Central Clinical Hospital of the Ministry of the Interior, Warsaw, Poland

Centre of Postgraduate Medical Education in the Department of Dermatology, the Central Clinical Hospital of the Ministry of the Interior, Warsaw, Poland

Department of Dermatology, Central Clinical Hospital of the Ministry of National Defence, Military Institute of Health Services, Warsaw, Poland

Adv Dermatol Allergol 2021; XXXVIII (2): 193-197

DOI: https://doi.org/10.5114/ada.2021.106195

Online publish date: 2021/05/22

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Localized scleroderma is an inflammatory disease causing sclerosis of the skin. The aetiology and pathogenesis of localized scleroderma remain unclear. Localized scleroderma is considered a genetically driven disease. It is not well understood if genetic factors or environmental exposure individually can cause its development or if their interaction is needed to trigger the disease. Some authors postulate that familial clustering is evidence of a hereditary disease. Familial localized scleroderma has been rarely reported and is a case worth studying. We present the review of literature on this subject with 3 additional cases of familial localized scleroderma with paediatric onset.

keywords:

Familial localized scleroderma with paediatric onset: a review

Ida Yurtsever 1 , Małgorzata Łukomska 1 , Piotr Sobolewski 2 , Elżbieta Szymańska 2 , Witold Owczarek 3 , Irena Walecka 2

morphea, localized scleroderma, familial, paediatric onset, juvenile

Ida Yurtsever

¹

,

Małgorzata Łukomska

¹

,

Piotr Sobolewski

²

,

Elżbieta Szymańska

²

,

Witold Owczarek

³

,

Irena Walecka

²