From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction

Iwona Gorczyca-Głowacka; Łukasz Nawacki; Magdalena Dolecka-Ślusarczyk; Agnieszka Ciba-Stemplewska; Stanisław Głuszek

doi:10.5114/ms.2024.145773

eISSN: 2300-6722
ISSN: 1899-1874

Medical Studies/Studia Medyczne

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1/2025
vol. 41

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abstract:

Review paper

From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction

Iwona Gorczyca-Głowacka

¹

,

Łukasz Nawacki

¹

,

Magdalena Dolecka-Ślusarczyk

¹

,

Agnieszka Ciba-Stemplewska

¹

,

Stanisław Głuszek

¹

Collegium Medicum, Jan Kochanowski University, Kielce, Poland

Medical Studies/Studia Medyczne 2025; 41 (1): 45–52

DOI: https://doi.org/10.5114/ms.2024.145773

Online publish date: 2025/01/31

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AMA

Gorczyca-Głowacka I, Nawacki Ł, Dolecka-Ślusarczyk M, Ciba-Stemplewska A, Głuszek S. From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction. Medical Studies/Studia Medyczne. 2025;41(1):45-52. doi:10.5114/ms.2024.145773.

APA

Gorczyca-Głowacka, I., Nawacki, Ł., Dolecka-Ślusarczyk, M., Ciba-Stemplewska, A.,  & Głuszek, S. (2025). From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction. Medical Studies/Studia Medyczne, 41(1), 45-52. https://doi.org/10.5114/ms.2024.145773

Chicago

Gorczyca-Głowacka, Iwona, Łukasz Nawacki, Magdalena Dolecka-Ślusarczyk, Agnieszka Ciba-Stemplewska,  and Stanisław Głuszek. 2025. "From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction". Medical Studies/Studia Medyczne 41 (1): 45-52. doi:10.5114/ms.2024.145773.

Harvard

Gorczyca-Głowacka, I., Nawacki, Ł., Dolecka-Ślusarczyk, M., Ciba-Stemplewska, A.,  and Głuszek, S. (2025). From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction. Medical Studies/Studia Medyczne, 41(1), pp.45-52. https://doi.org/10.5114/ms.2024.145773

MLA

Gorczyca-Głowacka, Iwona et al. "From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction." Medical Studies/Studia Medyczne, vol. 41, no. 1, 2025, pp. 45-52. doi:10.5114/ms.2024.145773.

Vancouver

Gorczyca-Głowacka I, Nawacki Ł, Dolecka-Ślusarczyk M, Ciba-Stemplewska A, Głuszek S. From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction. Medical Studies/Studia Medyczne. 2025;41(1):45-52. doi:10.5114/ms.2024.145773.

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Metabolic dysfunction-associated steatotic liver disease (MASLD) is common, affecting a quarter of the population. The pathogenesis of this disease is multifactorial and has been well known for years. After 40 years of using the binding definition of non-alcoholic fatty liver disease (NAFLD), in 2020 new criteria for the diagnosis of metabolic dysfunction-associated fatty liver disease (MAFLD) were proposed, which significantly simplified the diagnosis of the disease, and in 2023 another division of steatotic liver disease (SLD) was proposed based on the aetiology of the disease. The diagnosis of MASLD is clinically important because the presence of this disease significantly influences the prognosis related not only to hepatic but, above all, cardiovascular events.

keywords:

From NAFLD to MASLD – a new approach for the definition of fatty liver disease associated with metabolic dysfunction

Iwona Gorczyca-Głowacka 1 , Łukasz Nawacki 1 , Magdalena Dolecka-Ślusarczyk 1 , Agnieszka Ciba-Stemplewska 1 , Stanisław Głuszek 1

metabolic syndrome, obesity, diabetes mellitus, steatotic liver disease

Iwona Gorczyca-Głowacka

¹

,

Łukasz Nawacki

¹

,

Magdalena Dolecka-Ślusarczyk

¹

,

Agnieszka Ciba-Stemplewska

¹

,

Stanisław Głuszek

¹