eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
3/2020
vol. 71
 
Share:
Share:
more
 
 
abstract:
Original paper

Gastrointestinal stromal tumors of the colon and rectum

Alexandra Roşulescu
1, 2
,
Nicolae Cătălin Pechianu
1, 3, 4
,
Monica Hortopan
1
,
Mihaela Mihai
1
,
Simona Olimpia Dima
4, 5
,
Cezar Stroescu
5
,
Radu Zamfir
5
,
Vladislav Braşoveanu
2, 5
,
David Leonard
5
,
Cătălin Vasilescu
2, 5
,
Irinel Popescu
3, 4, 5
,
Vlad Herlea
1, 3, 4

1.
Department of Pathology, Fundeni Clinical Institute, Bucharest, Romania
2.
“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3.
“TituMaiorescu” University, Faculty of Medicine, Bucharest, Romania
4.
Center of Excellence for Translational Medicine, Fundeni Clinical Institute, Bucharest, Romania
5.
Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania
Pol J Pathol 2020; 71 (3): 200-206
Online publish date: 2020/10/25
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Gastrointestinal stromal tumors (GISTs) are rare neoplasms, colorectal location being met in less than 5% of cases. Knowledge about this site related particularities are limited.

The aim of this study is to present our experience with colorectal GISTs between 2005 and 2018 from the clinical, morphological, and immunohistochemical perspectives, with emphasis on prognostic factors.

From a total of 203 gastrointestinal stromal tumors registered, 12 were colorectal (6%). The number of colonic tumors surpassed that of the rectum (9 : 3) and on the right side were registered more cases than on the left side (6/3). 9 were primary tumors and 3 were recurrences. Men and women were represented equally and the age range was between 22 and 76. Tumor dimensions varied between 0.5 and 14 cm. Microscopically, spindle cell type was dominant. Mitotic rate was variable between 1 and 115/50HPFs. Accordingly, for primary tumors progression risks were assigned (low risk: 2 cases, intermediate risk: 3 cases and high risk: 4 cases). All GISTs were CD117 and DOG1 positive. Four of the patients died of the disease.
keywords:

gastrointestinal stromal tumor, colon, rectum, histopathology, immunohistochemistry

Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe