Advances in Dermatology and Allergology
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eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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Original paper

Globules in pigmented lesions: dermoscopic and pathomorphological correlation

Barbara Olędzka
1, 2
,
Michał Piątkiewicz
1
,
Elżbieta Kowalska-Olędzka
2, 3
,
Adam Gałązka
2
,
Anna Nasierowska-Guttmejer
4
,
Katarzyna Kisiel
2, 3
,
Magdalena Misiak-Gałązka
2, 3

  1. Medical Faculty, Medical University of Warsaw, Poland
  2. Evimed Medical Center, Warsaw, Poland
  3. Maria Skłodowska-Curie Medical Academy, Warsaw, Poland
  4. Lazarski University, Warsaw, Poland
Adv Dermatol Allergol
DOI: https://doi.org/10.5114/ada.2026.161826
Online publish date: 2026/05/16
Article file
- Globules in pigmented - Kowalska-Oledzka.pdf  [1.61 MB]
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1. Bowling J. Diagnostic Dermoscopy. The Illustrated Guide 2012; 15-34.
2. Wilkinson D, Argenziano G, Lallas A, et al. The Definitive Guide Dermoscopy & Diagnosis of Benign and Malignant Skin Lesions. 41-58
3. Garbe C, Amaral T, Peris K, et al.; European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC). European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024. Eur J Cancer 2025; 215: 115152.
4. Ilut PA, Camela E, Lallas K, et al. The natural evolution of nevi with peripheral globules. Dermatology 2023; 239: 760-7.
5. Kittler H, Seltenheim M, Dawid M, et al. Frequency and characteristics of enlarging common melanocytic nevi. Arch Dermatol 2000; 136: 316-20.
6. İlhan Erdil D, Koku Aksu AE, Turgut Erdemir VA, et al. Dermoscopic monitoring of pediatric melanocytic nevi regarding pattern and diameter changes. An Bras Dermatol 2024; 99: 833-9.
7. Reiter O, Chousakos E, Kurtansky N, et al. Association between the dermoscopic morphology of peripheral globules and melanocytic lesion diagnosis. J Eur Acad Dermatol Venereol 2021; 35: 892-9.
8. Moraes AFA, Blumetti TCMP, Pinto C, et al. Melanoma with peripheral globules: clinical and dermatoscopic features. J Am Acad Dermatol 2022; 87: 567-72.
9. Lallas A, Paschou E, Manoli SM, et al. Dermatoscopy of melanoma according to type, anatomic site and stage. Ital J Dermatol Venerol 2021; 156: 274-88.
10. Xu J, Gupta K, Stoecker WV, et al. Analysis of globule types in malignant melanoma. Arch Dermatol 2009; 145: 1245-51.
11. Avcı C, Kaşıkçı M, Lebe B, et al. Diagnostic performance of dermoscopy for distinguishing early melanomas and intermediate melanocytic lesions from low-grade dysplastic nevi. J Cutan Med Surg 2025; 29: 452-9.
12. Pampín-Franco A, Gamo-Villegas R, Floristán-Muruzábal U, et al. Melanocytic lesions with peripheral globules: results of an observational prospective study in 154 high-risk melanoma patients under digital dermoscopy follow-up evaluated with reflectance confocal microscopy. J Eur Acad Dermatol Venereol 2021; 35: 1133-42.
13. Lazaridou E, Fotiadou C, Apalla Z. Melanocytic lesions with peripheral globules: still a pitfall in the differential diagnosis of melanoma. J Eur Acad Dermatol Venereol 2021; 35: 1040.
14. Avcı C, Akın G, Lebe B, et al. Can we manage the melanocytic lesions with peripheral globules according to the grade of dysplasia? Australas J Dermatol 2024; 65: 358-68.
15. Jegou MH, Huet P, Penchet I. Mélanome en thèques [Nested melanoma]. Ann Dermatol Venereol 2017; 144: 60-4. French.
16. Argenziano G, Briatico G, Brancaccio G, et al. Clinical clues to avoid missing melanoma when morphology is not enough. Dermatol Pract Concept 2021; 11: e2021143.
17. Argenziano G, Soyer HP, Chimenti S, et al. Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet. J Am Acad Dermatol 2003; 48: 679-93.
18. Zalaudek I, Grinschgl S, Argenziano G, et al. Age-related prevalence of dermoscopy patterns in acquired melanocytic naevi. Br J Dermatol 2006; 154: 299-304.
19. Lallas A, Apalla Z, Ioannides D, et al. International Dermoscopy Society. Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society. Br J Dermatol 2017; 177: 645-55.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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