Pediatric Endocrinology Diabetes and Metabolism
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eISSN: 2083-8441
ISSN: 2081-237X
Pediatric Endocrinology Diabetes and Metabolism
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Case report

Horner’s syndrome in a 16-year-old patient during diabetic ketoacidosis

Marta Baszyńska-Wilk
1
,
Julia Przybylak-Ortega
1
,
Iga Cytrynowicz
1
,
Anna Świercz
1
,
Elżbieta Moszczyńska
1

  1. Department of Endocrinology and Diabetology, The Children’s Memorial Health Institute, Warsaw, Poland
Pediatr Endocrinol Diabetes Metab 2026; 32
DOI: https://doi.org/10.5114/pedm.2026.158648
Online publish date: 2026/01/21
Article file
- 0401_Horner’s syndrome.pdf  [0.76 MB]
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1. Bialo SR, Agrawal S, Boney CM, et al. Rare complications of pediatric diabetic ketoacidosis. World J Diabetes 2015; 6: 167–174. doi: 10.4239/wjd.v6.i1.167.
2. Barrea C, Vigouroux T, Karam J, et al. Horner Syndrome in Children: A Clinical Condition with Serious Underlying Disease. Neuropediatrics 2016; 47: 268–272. doi: 10.1055/s-0036-1584085.
3. Reede DL, Garcon E, Smoker WR, Kardon R. Horner’s syndrome: clinical and radiographic evaluation. Neuroimaging Clin N Am 2008; 18: 369–385, doi: 10.1016/j.nic.2007.11.003.
4. Cahill JA, Ross J. Eye on children: acute work–up for pediatric Horner’s syndrome. case presentation and review of the literature. J Emerg Med 2015; 48: 58–62. doi: 10.1016/j.jemermed.2014.07.041.
5. Smith SA, Smith SE. Bilateral Horner’s syndrome: detection and occurrence. J Neurol Neurosurg Psychiatry 1999; 66: 48–51. doi: 10.1136/jnnp.66.1.48.
6. Pishdad GR, Pishdad P, Pishdad R. Pupillary autonomic neuropathy simulating partial Horner syndrome in diabetes mellitus and its reversal with control of blood glucose. J Neuroophthalmol 2008; 28: 241–242. doi: 10.1097/WNO.0b013e31818333ab.
7. Baszyńska-Wilk M, Wysocka-Mincewicz M, Świercz A, Świderska J, Marszał M, Szalecki M. Peripheral Neuropathy as a Complication of Diabetic Ketoacidosis in a Child with Newly Diagnosed Diabetes Type 1: A Case Report. J Clin Res Pediatr Endocrinol 2018; 10: 289–293. doi: 10.4274/jcrpe.5374.
8. Foster JR, Morrison G, Fraser DD. Diabetic ketoacidosis–associated stroke in children and youth. Stroke Res Treat 2011; 2011: 219706. doi: 10.4061/2011/219706. 
9. Xie J, Yu X, Chen L, et al. Whether coagulation dysfunction influences the onset and progression of diabetic peripheral neuropathy: A multicenter study in middle–aged and aged patients with type 2 diabetes. CNS Neurosci Ther 2024; 30: e70040. doi: 10.1111/cns.70040.
10. Yang Y, Zhao B, Wang Y, et al. Diabetic neuropathy: cutting–edge research and future directions. Signal Transduct Target Ther 2025; 10: 132.  doi: 10.1038/s41392-025-02175-1.
11. Gibbons CH, Freeman R. Treatment–induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes. Brain 2015; 138: 43–52. doi: 10.1093/brain/awu307. 
12. Iguchi Y, Mori K, Koike H, et al. Hypophosphataemic neuropathy in a patient who received intravenous hyperalimentation. J Neurol Neurosurg Psychiatry 2007; 78: 1159–1160. doi: 10.1136/jnnp.2006.108720.

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