ISSN: 2451-0629
Archives of Medical Science - Atherosclerotic Diseases
Current volume Archive About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
Official journal of the International Lipid Expert Panel (ILEP)
CALL FOR PAPERS
1/2020
vol. 5
 
Share:
Share:
more
 
 
abstract:
Clinical research

Is it possible to predict atherosclerosis in the ascending aorta by the patient’s lipid panel?

İsmail Haberal
1
,
Mehmet Ali Yesiltas
2
,
Ahmet Ozan Koyuncu
1
,
Sebnem Batur
3
,
Sadiye Deniz Ozsoy
1
,
Hülya A.K. Yilmaz
4
,
Aysim Buge
3

1.
Department of Cardiovascular Surgery, Institute of Cardiology, Istanbul University Cerrahpasa, Istanbul, Turkey
2.
Department of Cardiovascular Surgery, Bakırköy Dr.Sadi Konuk Training and Research Hospital, Istanbul, Turkey
3.
Department of Pathology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
4.
Department of Anesthesiology and Reanimation, Institute of Cardiology, Istanbul University Cerrahpasa, Istanbul, Turkey
Arch Med Sci Atheroscler Dis 2020; 5: e237–e244
Online publish date: 2020/09/14
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
Atherosclerosis is a chronic inflammatory event characterized by stiffness and thickening of the vascular walls. In our daily practice, we assume the atherosclerotic potential of the patient by following the total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglyceride levels (lipid panel). We aimed to understand the relation between the HDL, LDL, cholesterol levels and the atherosclerosis in large vascular structures such as the ascending aorta.

Material and methods
We have searched for atherosclerosis in the aortic tissue samples from 48 patients. It is a study in which we examine the correlation of preoperative cholesterol values (HDL, LDL, triglyceride, total cholesterol) by dividing the patients into two groups according to the presence of plaque.

Results
Forty-three (89.6%) male and 5 (10.4%) female patients between 39 and 81 years of age were included in the study. There was no statistically significant difference between the patients’ preoperative cardiovascular risk assessments. The free T3 values were within the normal range in all patients, but there was a difference that patients in the non-atherosclerosis group had lower values. There was no statistically significant difference between the two groups’ HDL, LDL, total cholesterol, or triglyceride parameters.

Conclusions
As a result, in our study, no significant difference was found between HDL-C, LDL-C, triglyceride, total cholesterol values and the pathological process of aortic atherosclerosis. As a result of this study, we believe that it was necessary to correct the error margins of these parameters. In addition, it required the need for a clearer laboratory parameter to demonstrate atherosclerosis.

keywords:

atherosclerosis, low-density lipoprotein cholesterol, lipid panel

Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe