eISSN: 2299-0054
ISSN: 1895-4588
Videosurgery and Other Miniinvasive Techniques
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vol. 14
Original paper

Laparoscopic and open repair for perforated duodenal ulcer: single-center experience

Suren Agho Stepanyan, Areg Artak Petrosyan, Hayk Hovhannes Safaryan, Hayk Henrik Yeghiazaryan, Andranik Yuri Aleksanyan, Vahe Mkrtich Hakobyan, Karen Tigran Papazyan, Mkrtich Hamlet Mkrtchyan

Videosurgery Miniinv 2019; 14 (1): 60–69
Online publish date: 2018/06/11
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Perforation is a dangerous complication of peptic ulcer disease and requires emergency surgical treatment. In recent decades laparoscopic repair of duodenal perforation has been widely used in emergency abdominal surgery.

To analyze laparoscopic and open surgical treatment of 120 consecutive patients with perforated duodenal ulcer.

Material and methods
The study included a group of 120 consecutive patients, operated on for perforated duodenal ulcer in a single institution. Laparoscopic or open repair with or without an omental patch was performed. The value of the Boey score was investigated in predicting the outcomes of treatment in the entire study group.

In 61 (50.8%) cases open repair was performed, in 56 (46.7%) cases laparoscopic repair, and in 3 (2.5%) cases conversion was performed. In the laparoscopy group the mean hospital stay was 5 days (range: 3–14), in the open group 11.7 days (range: 6–63), and in the conversion group 9.3 days (8–10) (p < 0.001). There was a significant difference between characteristics of patients in the laparoscopic groups: in the second period of laparoscopic procedures (2014–2017) the duration of the operation was significantly shorter and the number of postoperative complications was significantly lower than in the initial study group (2010–2013).

The laparoscopic approach is an effective method for treatment of perforated duodenal ulcer in selected cases. A number of 20–25 cases for the surgeon operating with the laparoscopic method is sufficient to achieve an acceptable level of expertise. More prospective randomized studies are needed to evaluate the effectiveness of laparoscopic repair of perforated duodenal ulcer.


laparoscopic surgery, peptic ulcer, peptic ulcer perforation

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